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    • Molecular Biophysics Unit (MBU)
    • Browsing Molecular Biophysics Unit (MBU) by Title
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    • Division of Biological Sciences
    • Molecular Biophysics Unit (MBU)
    • Browsing Molecular Biophysics Unit (MBU) by Title
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    Browsing Molecular Biophysics Unit (MBU) by Title

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      • Analyses Of Seine Protease Active Sites And Protein-Protein Interactions 

        Iengar, Prathima (2012-11-15)
      • Analysis Of Potential CIS Regulatory Elements In Prokaryotic And Eukaryotic Genomes 

        Raghavan, Sowmya (2013-07-22)
      • Analysis Of Protein Evolution And Its Implications In Remote Homology Detection And Function Recognition 

        Gowri, V S (2009-07-22)
        One of the major outcomes of a genome sequencing project is the availability of amino acid sequences of all the proteins encoded in the genome of the organism concerned. However, most commonly, for a substantial proportion ...
      • Analysis Of Structural And Functional Types Of Protein-Protein Interactions 

        Nambudiry Rekha, * (2011-10-19)
      • Aromatic Interactions In Peptides : Designed Helices And β-Hairpins 

        Mahalakshmi, R (2009-04-15)
        Design of complex protein folds requires complete understanding of the stereochemical principles that govern polypeptide chain folding. Extensive studies on design and synthesis of specific secondary structures like ...
      • Biochemical And Molecular Insights Into β-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) From Plasmodium Falciparum 

        Kumar, Shailendra (2008-10-14)
        Malaria, caused by Plasmodium, is one of the most devastating infectious diseases of the world in terms of mortality as well as morbidity (WHO, 2002). The development of resistance in the Plasmodium falciparum against the ...
      • Biochemical, Biophysical and Evolutionary Perspectives of Zinc Finger Proteins in Mycobacterium smegmatis 

        Ghosh, Subho (2018-05-21)
        Transcription is a major step in expression of genes of a given organism. Due to environmental constrains this step must be regulated in the favour of the sustenance and growth of the organism. Here comes the relevance of ...
      • Biophysical Studies on Mycobacterium Tuberculosis σ Factor – Regulatory Protein Complexes 

        Jamithireddy, Anil Kumar
        Adaptation to external environmental conditions is essential for the survival of a bacterial cell. Bacteria have thus evolved multiple mechanisms to sense environmental stimuli and to couple this information into an ...
      • Biophysical Studies On The Plastic And Cooperative Properties Of Single Voltage Gated Na+ And Leak K+ Ion Channels 

        Nayak, Tapan Kumar (2011-03-08)
        Ion channels are fundamental molecules in the nervous system that catalyze the flux of ions across the cell membrane. There are mounting evidences suggesting that the kinetic properties of ion channels undergo activity-dependent ...
      • CcdB : Stability, folding and application to design novel antibacterials 

        Bhowmick, Jayantika
        The primary amino acid sequence typically dictates the ultimate conformation of the protein. Mutations in the sequence demonstrate neutral, positive or negative effects on the structure-function relationship of the protein. ...
      • Cell Surface Of Mycobacterium Smegmatis At The Stationary Phase : Regulation Of Gene Expression 

        Mukherjee, Raju (2009-05-21)
        Tuberculosis remains one of the oldest diseases known to mankind but still persists as a very major risk. Discovery of several antimycobacterials was marked by a steady decline in the active cases of pulmonary tuberculosis. ...
      • Characterization Of Carbohydrate Specificity And Primary Structure Of the B-cell Mitogen, Artocarpin, From Artocarpus Integrifolia Seeds 

        Geetha Rani, P (2011-11-17)
      • Cholinergic-receptor-independent modulation of intrinsic properties of subicular neurons through inhibition of hyperpolarization-activated cyclic nucleotide-gated channels 

        Vasnik, Sonali
        Acetylcholine release is vital in tuning the hippocampal theta oscillations. Subiculum, the output region of the hippocampus endowed with different neuronal subtypes, also generates theta oscillations during arousal and ...
      • Components Of Fatty Acid Synthesis In Plasmodium Falciparum 

        Sharma, Shilpi (2008-10-17)
        The disease malaria afflicts more than a billion people and kills almost one to three million of them every year. Of the four species of Plasmodium affecting man viz., P. falciparum, P. vivax, P. ovale and P. malariae, ...
      • Computational Analyses of Protein Structure and Immunogen Design 

        Patel, Siddharth (2018-08-20)
        The sequence of a polypeptide chain determines its structure which in turns determines its function. A protein is stabilized by multiple forces; hydrophobic interaction, electrostatic interactions and hydrogen bond formation ...
      • Computational Analyses Of Proteins Encoded In Genomes Of Pathogenic Organisms : Inferences On Structures, Functions And Interactions 

        Tyagi, Nidhi (2015-02-04)
        The availability of completely sequenced genomes for a number of organisms provides an opportunity to understand the molecular basis of physiology, metabolism, regulation and evolution of these organisms. Significant ...
      • Computational And Biochemical Studies On The Enzymes Of Type II Fatty Acid Biosynthesis Pathway : Towards Antimalarial And Antibacterial Drug Discovery 

        Kumar, Gyanendra (2009-08-13)
        Malaria, caused by the parasite Plasmodium, continues to exact high global morbidity and mortality rate next only to tuberculosis. It causes 300-500 million clinical infections out of which more than a million people succumb ...
      • Computational And Experimental Studies On Protein Structure, Stability And Dynamics 

        Adkar, Bharat V (2014-08-18)
        The work in this thesis focuses on the study of three main aspects of proteins, viz, Protein structure, stability, and dynamics. Chapter 1 is a general introduction to the topics studied in this thesis. Chapter 2 deals ...
      • Computational Investigation of Heterogeneous Lateral Organisation in Biological Membrane 

        Iyer, Sahithya S
        The study of lateral heterogeneity on membrane surface has come a long way from the fluid mosaic model. Simulations and experimental studies have observed non-random mixing of lipids and proteins in the membrane. In this ...
      • Computational Studies On Eosinophil Associated Ribonucleases : Insights Into Dynamics And Catalysis Through Molecular Dynamics Simulations 

        Sanjeev, B S (2011-05-11)

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