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Identification, Structural and Functional Characterisation of the Molecule that Induces Asymmetric Cell Division in Mycobacteria
(2017-12-03)
Phenotypic heterogeneity in terms of cell size, morphology, and metabolic status, which are believed to help the population survive under stress conditions, is known in mycobacterial populations. Such population heterogeneity ...
Regulation of Leaf Margin Development by TOOTH/MIR160A in Arabidopsis Thaliana
(2017-11-13)
TOOTH/MIR160A regulates leaf margin outgrowth in Arabidopsis thaliana
Unlike animals, a striking aspect of the plant development is that they have evolved a flexible pattern of post embryonic development. This exposes ...
The Role of Initiation Factor 3 : Insights from E. Coli, Mitochondria and Mycoplasma
(2018-01-07)
The process of translation initiation is the most highly regulated step of protein synthesis. In bacteria, three initiation factors (IF1, IF2 and IF3) play crucial roles during initiation. IF3 acts as an anti-association ...
Functional Characterization of Saccharomyces Cerevisiae SUB1 in Starvation Induced Sporulation Response
(2017-12-12)
Among the various external signals perceived by yeast cells, nutrient availability is a condition to which these cells show a highly diverse biological response. Diploid cells in response to different nutritional stress ...
Role of SIRT6 in Myofibroblast Cell Death
(2018-01-10)
Cardiovascular diseases are one of the leading causes of mortality. A common denominator across most of the cardiovascular diseases like diabetic cardiomyopathy, hypertrophic cardiomyopathy, myocardial infarction and dilated ...
Functional Characterization of RFL as a Regulator of Rice Plant Architecture
(2018-03-09)
Poaceae (or Gramineae) belong to the grass family and is one of the largest families among flowering plants on land. They include some of the most important cereal crops such as rice (Oryza sativa), barley (Hordeum vulgare), ...
Genetics of Glioma : Transcriptome and MiRNome Based Approches
(2018-03-26)
Glioma, the tumor of glial cells, is one of the common types of primary central nervous system (CNS) neoplasms. Astrocytoma is the most common of all gliomas and originates from astrocytic glial cells. Astrocytoma tumors ...
Topoisomerases from Mycobacteria : Insights into the Mechanism, Regulation and Global Modulatory Functions
(2018-03-09)
The eubacterial genome is maintained in a negatively supercoiled state which facilitates its compaction and storage in a small cellular space. Genome supercoiling can potentially influence various DNA transaction processes ...
Developmental Basis and Diversity of Polar Growth Patterns in Leaves
(2018-03-06)
Growth polarity in leaves – a final discussion
Insights into the growth processes of leaf lamina have come from studies on several species including Arabidopsis, Antirrhinum, tobacco and maize. A feature common to the ...
Insights into Occurrence and Divergence of Intrinsic Terminators and Studies on Rho-Dependent Termination in Mycobacterium Tuberculosis
(2018-04-11)
Two mechanisms, intrinsic and factor-dependent, have evolved for accomplishing the termination of transcription in eubacteria. In this thesis, the first chapter is an introduction to the topic that presents what is known ...