Browsing Microbiology and Cell Biology (MCB) by thesis submitted date"2009"
Now showing items 1-15 of 15
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Antimicrobial Peptides And Salmonella Pathogenesis
(2011-02-07)Chapter-I Introduction The bacteria known as Salmonellae are gram-negative, rod-shaped intracellular pathogenic bacilli that belong to the family Enterobacteriacea and causes typhoid fever. Enteric fever or typhoid ... -
Functional Analysis Of DdRpb4 And DdRpb7, Two Subunits Of Dictyostelium Discoideum RNA Polymerase II
(2010-04-06)The process of eukaryotic transcription and its regulation has been an interesting area of research for decades. With more insights into the process of transcriptional regulation of genes, studies have revealed a ... -
Functional Characterization Of Rv0754(PE_PGRS11) : A Multifunctional PE_PGRS Protein From Mycobacterium Tuberculosis
(2011-01-11)Mycobacterium tuberculosis, the causative agent of pulmonary tuberculosis, infects one-third of the world’s human population. Despite the multiplicity of antimicrobial mechanisms mounted by its host, M. tuberculosis shows ... -
Functions For OsMADS2 And OsMADS1 As Master Regulators Of Gene Expression During Rice Floret Meristem Specification And Organ Development
(2013-06-06)Plant reproductive development begins when vegetative shoot apical meristems change their fate to inflorescence meristems which develop floral meristems on the flanks. This process of meristem fate change and organ development ... -
Genetic And Biochemical Studies On Genes Involved In Leaf Morphogenesis
(2011-02-08)Much is known about how organs acquire their identity, yet we are only beginning to learn how their shape is regulated. Recent work has elucidated the role of coordinated cell division & expansion in determining plant ... -
Human Immune Response To Japanese Encephalitis Virus Guides Development Of Vaccines With Long Lasting Immunity
(2013-05-21)Chapter 1: Role of JEV NS1 in protective immunity and in immunopathology. Previous studies from our laboratory revealed T cell immunodominance of non structural proteins NS3 and NS1 during natural JEV infections in humans ... -
Lip Y, The PE Family Triacylglycerol Hydrolase From Mycobacterium Tuberculosis : Functional Role Of The PE Domain And Immunogenicity
(2010-10-28)More human lives have been lost to tuberculosis than to any other disease and despite the availability of effective short course chemotherapy (DOTS) as well as the Bacilli Calmette Guerin (BCG) vaccine, tuberculosis continues ... -
Mechanism Of Ribosome Recycling In Eubacteria, And The Impact Of rRNA Methylations On Ribosome Recycling And Fidelity Of Initiation In Esherichia coli
(2009-12-09)The studies reported in this thesis address, firstly, aspects of ribosome recycling in eubacteria, and secondly, a preliminary characterization of an EFG-like locus from Mycobacterium smegmatis. A hitherto unsuspected role ... -
Regulation and Characterization of Transcription Factor Activator Protein-2 Alpha (AP-2α)
(2018-02-11)Introduction AP2α is a 52 kDa retinoic acid inducible and developmentally regulated activator of transcription, which binds to the DNA in a sequence-specific manner. Transcription factor AP-2α was isolated from HeLa cells ... -
Rinderpest Virus Transcription : Functional Dissection Of Viral RNA Polymerase And Role Of Host Factor Ebp1 In Virus Multiplication
(2009-11-23)Rinderpest virus (RPV) belongs to the order Mononegavirale which comprises non segmented negative sense RNA viruses including human pathogens such as Measles, Ebola and Marburg virus. RPV is the causative agent of Rinderpest ... -
Stress Response In Salmonella And Its Role In Pathogenesis
(2011-02-08)Chapter: 1 Introduction Genus Salmonella is a Gram-negative rod shaped facultative anaerobic bacteria that can survive inside the host macrophages and cause persistent infection. Salmonella Typhimurium, Salmonella Typhi ... -
Structural, Functional And Transcriptional Analysis Of Nucleoside Diphosphate Kinase From Mycobacterium Smegmatis mc2 155
(2011-08-05)Maintenance of the levels of nucleoside triphosphates (NTPs) as well as their corresponding deoxy derivatives (dNTPs) is crucial to all growth and developmental processes. The enzyme nucleoside diphosphate kinase (NDK) ... -
Structure-Function Correlative Studies On The Biochemical Properties (Polymerisation, GTP binding, GTPase) Of Mycobacterial Cytokinetic Protein FtsZ In Vitro
(2010-03-26)FtsZ, the principal cell-division protein, polymerizes in GTP-dependent manner in vitro (Bramhill and Thompson, 1994; Mukherjee and Lutkenhaus, 1994; Rivas et al., 2000). FtsZ polymerization at the mid-cell site of bacterium ... -
Survival Strategies Of Salmonella Under Host Nitrosative Stress And Its Role In Pathogenesis
(2010-12-07)Chapter: 1 Introduction Genus Salmonella is a Gram-negative rod shaped facultative anaerobic bacteria that can survive inside the host macrophages and cause persistent infection. Salmonella Typhimurium, Salmonella Typhi ... -
Typhoidal And Non-Typhoidal Salmonella Serovars - A Comparartive Study
(2011-02-08)Chapter Introduction Salmonellae are gram negative bacteria that cause gastroenteritis and entericfever. S. enterica is divided into seven phylogenetic groups, subspecies 1, 2,3a, 3b, and 4, 6, 7. Subspecies1 includes ...