| dc.contributor.advisor | Prasad, Kavirayani R | |
| dc.contributor.author | Kesavulu, Gangarajulu | |
| dc.date.accessioned | 2025-01-23T05:18:46Z | |
| dc.date.available | 2025-01-23T05:18:46Z | |
| dc.date.submitted | 2024 | |
| dc.identifier.uri | https://etd.iisc.ac.in/handle/2005/6774 | |
| dc.description.abstract | The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri peptides without racemization. Further, the use of chiral pool tartaric acid and chiral furyl carbinols in the total synthesis of natural products is described. The targeted natural products include D-lyxo and xylo -Phytospingosines, sphingofungin B, AKML-B, ()-(6S,9R,10R)- Bovidic acid, Towards the synthesis of schulzeine B, and Phomopsolidones. | en_US |
| dc.language.iso | en_US | en_US |
| dc.relation.ispartofseries | ;ET00784 | |
| dc.rights | I grant Indian Institute of Science the right to archive and to make available my thesis or dissertation in whole or in part in all forms of media, now hereafter known. I retain all proprietary rights, such as patent rights. I also retain the right to use in future works (such as articles or books) all or part
of this thesis or dissertation | en_US |
| dc.subject | asymmetric synthesis | en_US |
| dc.subject | amino acid derivatives | en_US |
| dc.subject | total synthesis | en_US |
| dc.subject | purification | en_US |
| dc.subject | characterization | en_US |
| dc.subject | peptides | en_US |
| dc.subject.classification | Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry::Organic synthesis | en_US |
| dc.title | Asymmetric Synthesis of Amino Acid Derivatives and Total Synthesis of Biologically Active Natural Products | en_US |
| dc.type | Thesis | en_US |
| dc.degree.name | PhD | en_US |
| dc.degree.level | Doctoral | en_US |
| dc.degree.grantor | Indian Institute of Science | en_US |
| dc.degree.discipline | Faculty of Science | en_US |
