Browsing Department of Bioengineering (BE, Earlier known as BSSE) by Title
Now showing items 29-41 of 41
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Mechanistic insights into the effects and applications of shockwaves in prokaryotic and eukaryotic organisms
Shock waves are non-linear waves propagating at speeds greater than the speed of sound, with a unique characteristic of instantaneously increasing the pressure, temperature and density of the medium through which they ... -
Micro-carriers mediated bacteriophage delivery for targeting intracellular Mycobacterium tuberculosis infection and TB prevention
Tuberculosis (TB) is a debilitating infectious disease that afflicts 10 million people every year. Treatment is particularly challenging due to prolonged treatment duration (4-6 months) consisting of an oral regimen of 4 ... -
Molecular determinants of self-assembly of the pore forming toxin Cytolysin A
Pore forming toxins (PFTs) belong to a class of bacterial exotoxins that disrupt the biological membrane barrier by formation of nanopores. These toxins are central to the virulence of pathogens such as S. pneumoniae, ... -
Multistability in cellular differentiation enabled by three and four node mutually repressive regulatory networks: A case study of CD4+ T-cell decision making
Cellular differentiation is controlled by the complex dynamics of gene regulatory networks (GRNs), often featuring multistability, where multiple stable states represent different phenotypes. A common example is the toggle ... -
New Dimension in Senescence: Unraveling Cellular Senescence in Three-Dimensional Scaffolds
Aging is a ubiquitous process that results in the progressive and irreversible loss of function. It is induced by accumulating damage caused by a variety of stressors, both internal and external. Although the advancement ... -
PLGA Based Drug Carriers for Treatment of Osteoarthritis
Osteoarthritis (OA) has affected nearly 22-39% of the Indian population and remains one of the most common musculoskeletal disorders that affects articular joints. Post-traumatic osteoarthritis, which develops following ... -
Porous Polymeric Membranes with Engineered Surfaces for Water Remediation
Access to safe drinking water is one of the greatest challenges that have afflicted people across the globe. Approximately 1.2 billion people do not have access to safe drinking water while 2.6 billion have no access to ... -
Raman Microspectroscopic Studies on Differentiating Bacteria, Detecting Antimicrobial Resistance and Delineating Biomarkers of Sepsis
Over the last few decades, the development of several new techniques as well as sophisticated instruments have contributed to a better understanding of biological systems. Among these, Raman spectroscopy has emerged as an ... -
Resolvin D1-loaded Liposomal Nanocarriers for the Treatment of Osteoarthritis
Osteoarthritis (OA) is the most common disorder of the joints and currently affects >300 million patients worldwide. In this disease, the articulating cartilage undergoes progressive damage which leads to severe pain and ... -
The Role of Basal Ganglia and Redundancy in Supervised Motor Learning
Human sensorimotor control can achieve highly reliable movements under circumstances of noise, redundancy, uncertainty, and sensory delays. Our ability to achieve reliable and accurate movements is in the fact we have a ... -
Role of Fiber Orientations in the Mechanobiology of Cells under Stretch
Fiber reinforcement plays an important role in the structure and function of biological materials. Soft connective tissues in human body like artery, heart tissues, skin etc. exhibit anisotropic material responses due to ... -
Tailored Xylitol-based Biodegradable Polymers for Tissue Engineering and Drug Delivery
Tissue regeneration is an intricate physiological phenomenon that involves the interplay of various factors to restore tissue formation and function. Diseased or damaged tissues have often been replaced with synthetic ... -
Towards a Better Understanding of the Interaction between Phagocytic Immune Cells and Synthetic Particulates
Particulate technology has transformed the field of diagnostic and therapeutic medicine due to the ability of particulates to provide better contrast in various imaging modalities and improve the targeting of therapeutic ...