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    Browsing Biochemistry (BC) by Title

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      • Delta-Aminolevulinic Acid Dehydratase From Plasmodium falciparum - Indigenous Vs Imported 

        Dhanasekaran, S (2011-05-02)
      • Determination of significance of SUMOylation of the Smc5/6 complex 

        Balagopal, Deepa
        The fascination of scientists to the Smc5/6 complex began in the 1990s, with the characterization of UV and γ radiation-sensitive rad18 mutant and its identification as a component of a novel Structural Maintenance of ...
      • Development and Characterization of a potent Tumor Necrosis Factor-alpha blocking agent 

        Jameei, Aida
        Tumor necrosis factor-α (TNFα), one of the major pro-inflammatory cytokines, plays a pivotal role in an effective inflammation process and immune response. TNFα interacts with two different receptors, TNFR1 and TNFR2, which ...
      • Development of an Immunodiagnostic Kit for Species Identification of Snake Bite and Studies on the Cross-Reacting Venom Antigens 

        De, Anindya Kanti (2018-02-11)
      • Developmental And Functional Regulation Of DNA Topoisomerase II in Postnatal Rat Testis 

        Bakshi, Rahul P (Indian Institute of Science, 2005-11-23)
        Characterization of the polyoma virus chromosome as a circular, double-stranded, supercoiled DNA (Weil and Vinograd, 1963; Vinograd et al.,-1965) made it apparent that the DNA enzymatic machinery faces a formidable problem ...
      • Diaminopropionate Ammonia Lyase : Characterization, Unfolding And Mechanism Of Inhibition By Aminooxy Compounds 

        Khan, Farida (2009-03-13)
        Diaminopropionate ammonia lyase (DAPAL) which belongs to the  class of PLP enzymes is reported only from prokaryotes. It is involved in the removal of two amino groups from its substrate, diaminopropionate, to form ammonia ...
      • Differential Role Of FSH : A Study Using Sertoli Cells And Epididymal Cells 

        Chitra Lekha, * (2011-08-19)
      • DNA Cleavage By Type III Restriction Enzyme EcoP151 : Properties, Mechanism And Application 

        Raghavendra, N K (2011-08-19)
      • DNA Double-Strand Break Repair : Molecular Characterization of Classical and Alternative Nonhomologous End Joining in Mitochondrial and Cell-free Extracts 

        Kumar, Tadi Satish (2018-04-05)
        Maintenance of genomic integrity and stability is of prime importance for the survival of an organism. Upon exposure to different damaging agents, DNA acquires various lesions such as base modifications, single-strand ...
      • DNA Mismatch Repair In Haemophilus Influenzae : Characterization Of MutH, L, S And Their Interaction 

        Joseph, Nimesh (2011-05-03)
      • Dual Sites For Heme Biosynthesis In The Malarial Parasite 

        Varadharajan, S (2011-05-02)
      • The dual-targeting of Saccharomyces cerevisiae Pso2 into the nucleus and mitochondria is regulated by post-translational modifications: Implications for organelle-specific DNA repair 

        Somashekara, S C
        The repair of DNA interstrand crosslinks (ICLs) involves the concerted action of multiple DNA repair pathways. In eukaryotes, ICLs are sensed and repaired by replication-coupled or replication-independent mechanisms in ...
      • Effect Of Glycodelin A On Cells Of The Immune System Insights Into GdA-Induced Signaling In Monocytes, B And NK Cells 

        Alok, Anshula (2010-04-06)
        Glycodelin is a 162 amino acid dimeric, glycosylated, secretory protein of the lipocalin superfamily. Its classification as a lipocalin(carriers of small hydrophobic molecules) is based mainly on the presence of lipocalin ...
      • Effect of Heat Exposure On Allogeneic Cytotoxic T Lymphocyte Responses in Mice 

        Sukumaran, M K (2018-03-01)
      • Elucidating the Roles of Lon Protease and its Substrate, MarA, in Response to salicylate and other Compounds in Escherichia coli 

        Bhaskarla, Chetana (2017-11-28)
        Cytosolic protein degradation is crucial for cellular homeostasis as it orchestrates protein turnover by destruction of misfolded, unstable and abnormal proteins. This process has two main stages: (i) an ATP-dependent stage ...
      • The Elucidation of the Mechanism of Meiotic Chromosome Synapsis in Saccharomyces Cerevisiae : Insights into the Function of Synaptonemal Complex, Hop1 and Red1, Proteins and the Significance of DNA Quadruplex Structures 

        Kshirsagar, Rucha (2017-12-03)
        Meiosis is a specialized type of cell division where two rounds of chromosome segregation follow a single round of DNA duplication resulting in the formation of four haploid daughter cells. Once the DNA replication is ...
      • Elucidation of the Role of Nse1, a RING Domain Containing Component of Smc5/6 complex, in Maintenance of Chromosome Stability in Saccharomyces cerevisiae 

        Wani, Saima Masood (2018-05-21)
        Structural Maintenance of Chromosomes (SMC) proteins are a highly conserved class of proteins required for the maintenance of genome stability and regulate nearly all aspects of chromosome biology. Eukaryotes, such as the ...
      • Establishment of human ectopic liver tissue in immunocompromised mice as a model for Hepatitis C Virus studies 

        Jayal, Priyanka
        Infection with hepatitis C virus (HCV) leads to an inflammatory condition which may progress to liver cirrhosis and in some cases, hepato-cellular carcinoma. Though, new drugs are being added to the list of HCV therapeutics, ...
      • Evaluation of Alternate DNA Structures at c-MYC Fragile Region Associated with t(8;14) Translocation And Role of GNG Motifs During G-quadruplex Formation 

        Das, Kohal (2017-10-11)
        Watson-Crick paired B-form DNA is the genetic material in most of the biological systems. Integrity of DNA is of utmost importance for the normal functioning of any organism. Various environmental factors, chemicals and ...
      • Evaluation Of The Efficacy Of DNA Vaccines For Japanese Encephalitis In A Murine Intracerebral Japanese Encephalitis Virus Challenge Model 

        Ashok, M S (Indian Institute of Science, 2005-12-05)
        Japanese encephalitis virus (JEV), a member of the family flaviviridae, is one of the most important pathogens of the developing countries, causing high mortality and morbidity amongst children. The present study is aimed ...

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