Browsing Biochemistry (BC) by Title
Now showing items 250-269 of 435
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Physiological And Exogenous Means of Regulating DNA Damage Response : Insights into Mechanisms of DNA Repair And Genomic Instability
(2017-09-23)Maintenance of genomic integrity with high fidelity is of prime importance to any organism. An insult which may result in compromised genome integrity is prevented or its consequences are monitored by advanced cellular ... -
Physiological Significance of Stop Codon Readthrough
Regulation of translation, the process by which ribosomes synthesize proteins from mRNAs, is critical to maintain cellular proteostasis. Dysregulation of translation is implicated in several neurodegenerative, metabolic, ... -
Primary structures and active site residues of sheep liver serine hydroxymethyltransferase
Serine hydroxymethyltransferase (SHMT), which catalyzes the hydroxymethyl transfer from serine to H4-folate, is a unique PLP-enzyme, different from aminotransferases, decarboxylases, racemases, and PLP-enzymes catalyzing ... -
Processing Of DNA Recombination And Replication Intermediates By Mycobacterium Tuberculosis RuvA And RuvB Proteins
(2013-06-14)Homologous recombination (HR) is a highly conserved cellular process involved in the maintenance of chromosomal integrity and generation of genetic diversity. Biochemical and genetic studies have suggested that HR is ... -
Production Of Anticancer Drug Taxol And Its Precursor Baccatin III By Fusarium Solani And Their Apoptotic Activity On Human Cancer Cell Lines
(2013-06-24)Taxol (generic name paclitaxel), a plant‐derived antineoplastic agent, was originally isolated from the bark of the Pacific yew, Taxus brevifolia. Obtaining taxol from this source requires destruction of trees. It has ... -
Production of taxol from Lasiodiplodia theobromae and biochemical characterization of its 10-deacetylbaccatin III-10-O-acetyltransferase enzyme and evaluation of anticancer activity of enzymatically synthesized baccatin III
Taxol (paclitaxel) originally identified from the inner bark of Taxus brevifolia, is a clinically approved anticancer drug for the treatment of various kinds of cancer, particularly ovarian cancer, breast cancer and Kaposi's ... -
Purification , active site interactions and partial primary structure of serine hydroxymethyltransferase from seedlings of trigonella foenum graecum
SHMT catalyzes the conversion of Ser to Gly by the transfer of a hydroxymethyl group to H?-folate to yield 5,10-CH?-H?-folate. This compound serves as a carrier of one-carbon units for the biosynthesis of a number of ... -
Purification and characterization of an acid protease from germinated sorghum (Sorghum Vulgare)
Abstract not available -
Regulation of carbon metabolism in Pichia pastoris by Mxr1p and identification of novel regulators
Pichia pastoris (a.k.a. Komagataella phaffii), a widely used yeast for recombinant protein production, is cultured under a variety of conditions ranging from shake flasks to large bioreactors employing minimal, chemically ... -
Regulation of Flagellar Motility in Giardia lamblia and Trichomonas vaginalis
Protozoan pathogens are responsible for infections that are highly prevalent, especially in developing and under-developed countries. Flagellar motility is exhibited by a variety of organisms ranging from bacteria to certain ... -
Regulation of Hepatic tryptophan pyrrolase under conditions of environmental stress
Abstract not available -
Regulation of RecA nucleoprotein filament stability by RecX and the effects of RecA-membrane interaction on the activities of RecA in mycobacteria
E. coli RecA is a multifunctional protein known to be associated with the cell membrane, forming foci often located at the cell poles, which gets redistributed along the length of the cell during SOS response. Several lines ... -
Regulation of the Expression of Ribosomal Proteins by Small Downstream ORFs
Eukaryotic mRNAs have historically been believed to harbour a single open reading frame (ORF). However, over the last decade, ribosome profiling has revealed extensive ribosome occupancy in the untranslated regions ... -
Regulation of the respiration function of brown adipose tissue mitochondria
Abstract not available