Browsing Biochemistry (BC) by Title
Now showing items 244-263 of 435
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Oxidative Stress In The Brain: Effects Of Hydroperoxides And Nitric Oxide On Glyceraldehyde 3-Phosphate Dehydrogenase And Phosphoinositide Cycle Enzymes
(Indian Institute of Science, 2005-09-01)In the aerobic cell, oxygen can be converted into a series of reactive metabolites, together called as "reactive oxygen species" (ROS). This large group include both radical and non-radical species such as superoxide anion ... -
Peptidase N, A Major Aminopeptidase Belonging To The M1 Family : Biochemical And Functional Implications
(2009-08-05)Intracellular protein degradation is required for maintaining the cellular proteome and regulating cellular processes. This pathway involves proximal ATP-dependent proteases that unfold and translocate proteins targeted ... -
Peroxisomal Targeting Of Pichia Pastoris Cytochrome C During Methanol And Fatty Acid Metabolism
(2011-03-08)Intracellular protein sorting plays a key role in the regulation of cellular metabolism, gene expression, signal transduction and a number of other cellular processes. Proteins targeted to specific cellular compartments ... -
Physico-chemical studies on hen's egg yolk lipovitellins and very low density lipoprotiens
The work described in this thesis can be broadly classified into two major sections namely, (1) Chemical studies, which describes the preparation of lipovitellins, fractionation of their protein components and comparison ... -
Physiological And Exogenous Means of Regulating DNA Damage Response : Insights into Mechanisms of DNA Repair And Genomic Instability
(2017-09-23)Maintenance of genomic integrity with high fidelity is of prime importance to any organism. An insult which may result in compromised genome integrity is prevented or its consequences are monitored by advanced cellular ... -
Physiological Significance of Stop Codon Readthrough
Regulation of translation, the process by which ribosomes synthesize proteins from mRNAs, is critical to maintain cellular proteostasis. Dysregulation of translation is implicated in several neurodegenerative, metabolic, ... -
Primary structures and active site residues of sheep liver serine hydroxymethyltransferase
Serine hydroxymethyltransferase (SHMT), which catalyzes the hydroxymethyl transfer from serine to H4-folate, is a unique PLP-enzyme, different from aminotransferases, decarboxylases, racemases, and PLP-enzymes catalyzing ... -
Processing Of DNA Recombination And Replication Intermediates By Mycobacterium Tuberculosis RuvA And RuvB Proteins
(2013-06-14)Homologous recombination (HR) is a highly conserved cellular process involved in the maintenance of chromosomal integrity and generation of genetic diversity. Biochemical and genetic studies have suggested that HR is ... -
Production Of Anticancer Drug Taxol And Its Precursor Baccatin III By Fusarium Solani And Their Apoptotic Activity On Human Cancer Cell Lines
(2013-06-24)Taxol (generic name paclitaxel), a plant‐derived antineoplastic agent, was originally isolated from the bark of the Pacific yew, Taxus brevifolia. Obtaining taxol from this source requires destruction of trees. It has ... -
Production of taxol from Lasiodiplodia theobromae and biochemical characterization of its 10-deacetylbaccatin III-10-O-acetyltransferase enzyme and evaluation of anticancer activity of enzymatically synthesized baccatin III
Taxol (paclitaxel) originally identified from the inner bark of Taxus brevifolia, is a clinically approved anticancer drug for the treatment of various kinds of cancer, particularly ovarian cancer, breast cancer and Kaposi's ... -
Purification , active site interactions and partial primary structure of serine hydroxymethyltransferase from seedlings of trigonella foenum graecum
SHMT catalyzes the conversion of Ser to Gly by the transfer of a hydroxymethyl group to H?-folate to yield 5,10-CH?-H?-folate. This compound serves as a carrier of one-carbon units for the biosynthesis of a number of ... -
Purification and characterization of an acid protease from germinated sorghum (Sorghum Vulgare)
Abstract not available -
Regulation of carbon metabolism in Pichia pastoris by Mxr1p and identification of novel regulators
Pichia pastoris (a.k.a. Komagataella phaffii), a widely used yeast for recombinant protein production, is cultured under a variety of conditions ranging from shake flasks to large bioreactors employing minimal, chemically ...