Browsing Biochemistry (BC) by Title
Now showing items 187-206 of 435
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Mechanistic Insights Into Heat Shock Protein 90 (Hsp90) Trans-splicing in Giardia lamblia
Hsp90 gene is conserved and encoded by a single ORF with none to many cis-spliced introns across the biological kingdom. Previous studies from our lab have shown that Hsp90 gene in Giardia lamblia has a split nature having ... -
Mechanistic Insights into Radioprotection by Caffeine and Understanding Impact of Caffeine on Nonhomologous End Joining: Implications in Cancer
Maintenance of genome integrity is of utmost importance for the survival of any organism. Genetic instability is usually associated with various disorders, and it often leads to premature aging and predisposition to various ... -
Mechanistic insights into the replication of Sesbania mosaic virus
The present thesis deals with the mechanism of replication of Sesbania mosaic virus (SeMV), which belongs to the genus sobemoviruses. Sobemoviruses are single stranded positive sense RNA viruses which infect both mono and ... -
Metabolic and Pharmacological Modulations During IFN-γ signaling
Interferons, initially discovered for their antiviral properties, play pivotal roles in various biological processes, including host defense against pathogens, tumor surveillance, and disease pathogenesis. Interferon-gamma ... -
Metabolic Regulation of Gametocytogenesis in Malaria
Plasmodium sp. is an obligate intracellular protozoan parasite causing malaria and is responsible for more than 500,000 human deaths annually. P. falciparum and P. vivax are the two major species causing malaria in humans. ... -
Metabolism of naphthalene and methylnaphthalenes in Pseudomonas putida : Elucidation of catabolic pathways and purification and properties of 1,2-Dihydroxynaphthalene dioxygenase
I. Polycyclic aromatic hydrocarbons (PAHs), which include naphthalene and alkyl-substituted naphthalenes, are universal products of combustion of organic matter. The mutagenic and carcinogenic nature of several PAHs makes ... -
Metabolism of phenolic acids in relation to the biosynthesis of ubiquinone and sterols
Abstract not available -
Metabolism of phenolic amines : degradation ofdl-synephrine by Arthrobacter synerphrium sp.Nov. Ph.D
Among the natural phenolic amines, those derived from phenylalanine form an important group and are sometimes distinguished as protoalkaloids. Although the role of phenolic amines in animal metabolism and their mode of ... -
Metabolism of protocatechnic acid in tecoma stans
This thesis encompasses the studies on the biosynthesis and degradation of protocatechuic acid in Tecoma stans. In the introduction, a brief survey of the role and metabolism of phenolic compounds in plants is given. In ... -
Modeling the CD8+ T cell response to solid tumors: A multi-scale immunoinformatics approach to prognosticating disease outcome
Robust CD8 T cell activity is crucial for anti-tumor immune response. CD8 T cells keep tumors in check using direct effector mechanisms that cause tumor death. The key to this activity is the recognition of tumor cells as ... -
Modulation of HMGCoA reductase activity by adenine nucleatides, iron and adrimycin.
Abstract not available