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Total Synthesis of Bio-active Natural Products Gabosines, Crassalactone C, Anamarine and Iriomoteolide 3a
(2018-01-03)
First chapter of the thesis describes the desymmetrization of the bis-dimethyl amide 1 derived from tartaric acid with vinyl Grignard reagents and subsequent reduction of the resultant -keto amides 2a-c to the -hydroxy ...
Synthesis of Glycosyl Amino Acids, Glyco Amino Acids & α-Amino γ-Lactams from Carbohydrate Derived Donor-Acceptor Cyclopropanes
(2017-11-22)
Synopsis
The thesis entitled “Synthesis of Glyco-amino-acids, Glycosyl-amino-acids, and α-Amino γ-Lactams from Carbohydrate Derived Donor-Acceptor Cyclopropanes” is divided into five chapters.
Chapter 1: Introduction ...
Stereochemical And Synthetic Investigations
(2017-05-25)
PART I
RESOLUTION AND DESYMMETRISATION
Chapter I. ‘A Novel Racemate Resolution’. This describes a novel resolution strategy as applied to racemic α-amino acids in the solid state. The strategy is based on the possibility ...
Design, Synthesis and Applications of Novel Thiosugars & Amino Acid Derivatives
(2018-03-03)
Glycosidases are carbohydrate processing essential enzymes necessary for the growth and development of all organisms such as intestinal digestion, post-translational processing of glycoproteins and the lysosomal catabolism ...
New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production
(2018-05-10)
The thesis entitled “New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production” encompasses design, computational calculations, and syntheses of diverse ...
Design and Development of Metal-free Cross Dehydrogenative Coupling Reactions for the Construction of C-S, C-O and C-C bonds
(2018-06-13)
The thesis entitled “Design and Development of Metal-Free Cross Dehydrogenative Coupling Reactions for the construction of C-S, C-O and C-C bonds” is divided into three Chapters. Chapter 1 is presented in five parts, which ...
Evolution of New Lipids and Molecular Gelators : Syntheses, Aggregation Properties and Applications
(2018-05-14)
The thesis entitled “Evolution of New Lipids and Molecular Gelators: Syntheses,
Aggregation Properties and Applications” elucidates the design, synthesis, aggregation properties and application of new lipids based on ...
Copper-Catalyzed Novel Oxidative Transformations : Construction of Carbon-Hetero Bonds
(2018-05-08)
The thesis entitled “Copper-Catalyzed Novel Oxidative Transformations: Construction of Carbon-Hetero Bonds” is divided into two main sections. Section A deals with the utility of azide as a nitrogen source for C-N bond ...
Organic Transformations in Water : Synthetic and Mechanistic Studies towards Green Methodologies
(2018-04-12)
This thesis entitled “Organic Transformations in Water: Synthetic and Mechanistic Studies towards Green Methodologies” is in two parts. Part-I describes various synthetic studies aimed at developing improved methodologies; ...