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Cp2Ti(III)Cl-Mediated Endo- and Exo-Radical Cyclization: Synthesis of a Tri-nor-guaiane Sesquiterpene Isoclavukerin A, Terpenoid Bicyclic Lactones and Synthetic Studies Towards the Total Synthesis of Scabrolide A
Radical cyclization strategy always gives an expedient access to complex molecular scaffolds present in many bioactive natural products. In this research work, a systematic study is undertaken to investigate the less ...
Asymmetric Synthesis of Amino Acid Derivatives and Total Synthesis of Biologically Active Natural Products
The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri ...
Iridium-Catalyzed Enantioselective Alkylation of Enols and Their Surrogates
This thesis, entitled “Iridium-Catalyzed Enantioselective Alkylation of Enols and their Surrogates” is divided into four chapters.
In Chapter 1, the examples of the utilization of vinyl azide as amide and ketone enolate ...
Employing Arynes in Unique Multicomponent Reactions and a Strain-Release Ene Reaction
Arynes are highly reactive electrophilic intermediates, extensively used for synthesizing various benzo-fused heterocycles and 1,2-disubstituted benzenes. Among the numerous reactions of arynes, multicomponent coupling ...
Bile Salts in Supramolecular Chemistry: Synthesis of Fluorescent Nanoclusters, Oxide Nanoflowers, and Anion Effect on Metallogels
In summary, we have explored an interesting pH-dependent sensitization of Tb(III) using methyl salicylate (MS) as a sensitizer in aqueous media. Methyl salicylate was found to be a specific sensitizer for Tb(III) but not ...
A Mitsunobu-Michael Reaction Sequence to N-Heterocyclic Variants and Ti(III)-Mediated Synthesis of Terpenoids and N-Fused Indoles
The research work delineates a flexible and novel route for the diastereoselective construction of diversely substituted N-heterocyclic variants as valuable scaffolds for natural products and pharmaceuticals, starting from ...