Browsing Organic Chemistry (OC) by Subject "Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry"
Now showing items 1-20 of 42
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2,3-Dideoxy Sugars in Glycoconjugations and Cyclic Oligosaccharide Synthesis
2,3- Dideoxy sugars are versatile synthons for organic synthesis. The applications are diverse in biological systems and organic synthesis. In the first part of the thesis, 2,3-unsaturated sugars are used for the ... -
Allylic Halogenation Route to Latent-Active Trans-Glycosylation of Allyl Glycoside Donors
Allylic halogenation of allyl glycosides as a new route to allyl glycoside donors in glycosylations is investigated in this thesis. Allyl functionality is one of the commonly adopted protecting groups to hydroxyl groups ... -
Analytical Applications of Bile Acid-derived Soft Materials
Supramolecular gels are soft materials with solid-like properties such as supporting weight and retaining shape; and some liquid-like features which make them injectable, printable, etc. On the other hand, lanthanide-based ... -
Asymmetric Catalysis, Transition metal catalysis, Allylation, Propargylic alkylation, Cooperative catalysis and nonadjacent stereocenter
Transition metal catalysis has transformed asymmetric synthesis by enabling precise control of stereocenters, essential for bioactive molecules. This thesis outlines a systematic investigation of stereochemical complexity ... -
Asymmetric Catalysis: From Atroposelective Organocatalysis to Iridium-Catalyzed Generation of Central Chirality
Thesis Abstract: This thesis, entitled as “Asymmetric Catalysis: From Atroposelective Organocatalysis to Iridium-Catalyzed Generation of Central Chirality” is divided into three chapters. Chapter 1, highlights the ... -
Breaking Symmetry – Organocatalytic Enantioselective Synthesis of Natural and Unnatural Ladderanes
Architecturally unique compounds produced by nature have remained a source of inspiration for organic chemists. Ladderane phospholipids (such as [5][3]PC and [3][3]PC), isolated in the year 2002 from anaerobic ammonium oxidizing ... -
C-H Bond Functionalization and Tandem Cyclization with Alkynoates and Maleimides Using Directing Group Strategy
The thesis presents manganese‒ and rhodium‒catalyzed C‒H bond activation and tandem cyclization reactions. These reactions lead to the construction of carbon‒carbon bonds using directing group strategy. The thesis is divided ... -
Carbon-Carbon and Carbon Heteroatom Bond Forming Reactions: From Organocatalysts to Quantum Dots
Butenolides containing stereogenic centers on the ring, are commonly encountered structural motifs, found in many natural products. Consequently, there has been considerable interest in efficient and stereoselective ... -
Construction of C-C bonds by C-H Activation: Rh(III)-Catalyzed reactions of Arenes and Heteroarenes with Maleimides and Allylic Alcohols
The thesis presents a few Rh-catalyzed C-H activations for the construction of C-C bonds. The difficulty of substitution or the arylation at the maleimide's double bond under C-H activation conditions prompted a detailed ... -
Construction of C-C Bonds by Photocatalysis via Radical Addition Cascade Cyclization (RACC): Synthesis of Heteroatom-Containing Small Molecules
The thesis presents photocatalytic methods for synthesizing small organic molecules at room temperature. The thesis is divided into four sections. Section A presents the general introduction to the thesis. Section B is ... -
Construction of Carbon-Heteroatom and Heteroatom-Heteroatom bonds using Iodine and Zinc catalysts
The thesis entitled “Construction of Carbon-Heteroatom and Heteroatom-Heteroatom bonds using Iodine and Zinc catalysts” has been divided into five chapters. Chapter 1 describes a general introduction to iodine, hyper-valent ... -
Delayed Luminescent Materials: Development and Exploration of Applications
Delayed luminescence (DL) refers to light emission that persists after the excitation source is removed. Differing from conventional fluorescence, DL has a considerably longer lifetime attributable to the slow exciton ... -
Design and Synthesis of New Delivery Vehicles for Anti- Cancer Therapeutics
The thesis entitled ‘‘Design and Synthesis of New Delivery Vehicles for Anti-Cancer Therapeutics’’ encloses the syntheses, characterization and bioactivity determination of the novel systems designed for achieving high ... -
Diastreoselective addition of Alkylidene succinimides to non-racemic sulfinimines; Towards the total synthesis of nakadomarin A
The thesis titled “Diastereoselective addition of alkylidene succinimides to non-racemic sulfinimines: Towards the total synthesis of (+)-nakadomarin A” describes a systematic study on the addition of sodium enolates of ... -
Diverse Applications of Luminescent Metallocholate Hydrogels
Supramolecular gels are soft materials consisting of a solid three-dimensional network with noncovalent interactions such as hydrophobic interactions, hydrogen bonding, cation-п, and п- п interactions. Due to their soft, ... -
Enantioselective Annulation Reactions: From Fischer Indolization to de novo Arene Construction
In summary, we have developed the first decarboxylative [4+2]-annulation of ethynyl benzoxazinanones with azlactones for the enantioselective synthesis of cyclic α-quaternary α-acylaminoamides.25 This direct and modular ... -
Engineering of Nanomaterials: Application in Antibacterial Activity, Bio-Analyte Detection and Environmental Remediation
Infectious diseases caused by pathogenic bacteria are creating a global health problem. In the recent report of World Health Organization (WHO), it has been mentioned that around 7 lacks people are dying each year worldwide ... -
Functionalized Nanomaterial and Metallocycle for Selective Antibacterial, Diagnosis, and Anti-cancer Activity
The evolution of drug resistant bacteria has become a severe threat to public health globally. The misuse of conventional antibiotics has led to the development of multi-drug resistant bacteria. Even though antibiotics ... -
Harnessing Strained Systems: Arynes, Donor Acceptor Cyclopropanes, and Bicyclobutanes in Annulations, Multicomponent Couplings and Insertion Reactions
More than a century ago, the discovery of aryne intermediates proved to be a valuable addition to the toolkit of organic chemists, enabling the synthesis of a diverse range of molecules using these electrophilic ... -
HBS Constrained Antiparallel β-Sheets and Flat Toroid Turns; Homoserine, Thioamide and 1,3-Thiazine Containing Peptidomimetics: Design, Synthesis, Conformational Analyses and applications
In chemical biology, short peptidomimetic biological active models have been widely used for anti-microbial activity, drug development, catalysis, and amyloidogenesis. In this thesis, I have synthesized several unnaturally ...