Browsing Organic Chemistry (OC) by Title
Now showing items 84-103 of 213
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Harnessing Strained Systems: Arynes, Donor Acceptor Cyclopropanes, and Bicyclobutanes in Annulations, Multicomponent Couplings and Insertion Reactions
More than a century ago, the discovery of aryne intermediates proved to be a valuable addition to the toolkit of organic chemists, enabling the synthesis of a diverse range of molecules using these electrophilic ... -
HBS Constrained Antiparallel β-Sheets and Flat Toroid Turns; Homoserine, Thioamide and 1,3-Thiazine Containing Peptidomimetics: Design, Synthesis, Conformational Analyses and applications
In chemical biology, short peptidomimetic biological active models have been widely used for anti-microbial activity, drug development, catalysis, and amyloidogenesis. In this thesis, I have synthesized several unnaturally ... -
Hybrid Nanostructured Materials from Bile Acid Derived Supramolecular Gels
(2018-06-13)Research activities towards the self-assembly of small organic molecules building blocks which lead to form supramolecular gel has increased extensively during the past two decades. The fundamental investigations of the ... -
Investigating the Intercarbonyl X...C' (X=O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of charge->II* Interactions. Synthesis and Characterization of Thioimidate Isostere Containing Peptidomimetics
(2018-02-06)This thesis entitled “Investigating the Intercarbonyl X···C′ (X = O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of Charge→π* Interactions. Synthesis and Characterization of Thioimidate Isostere ... -
Iodine and Copper Catalyzed Oxidative Cross Coupling Reactions : Design and Development of Carbon-Carbon and Carbon-Heteroatom Bond Forming Reactions
(2018-01-17)Design and Development of Carbon-Carbon and Carbon-Heteroatom Bond Forming Reactions” is divided into two sections. Section-A, contains two chapters, describes the catalytic ability of iodine for cross coupling reactions. ... -
Ireland-Claisen Rearrangement Based Strategy To Sesquiterpenes Containing Vicinal Quaternary Carbon Atoms
(2009-03-02)Among Nature's creation, terpenoids are more versatile and exciting natural products. In a remarkable display of synthetic ingenuity and creativity, nature has endowed terpenes with a bewildering array of carbocyclic ... -
Lanthanide Based Hydrogels in Sensing, Energy Transfer and Nanoparticle Synthesis
(2018-01-04)Chapter 1: Luminescence property of lanthanide and its applications Lanthanides are well-known for their unique luminescence property and have found widespread applications in sensing, bioimaging, lasers, optoelectronic ... -
Lanthanide-derived Photoluminescent Hydrogels for Analytical Screening of Norfloxacin, Ofloxacin, α-Chymotrypsin, and Gossypol
Supramolecular gels are soft substances made of elastic cross-linked three-dimensional network connected by noncovalent interactions such as hydrogen bonds, hydrophobic interactions, donor-acceptor interactions, π- π ... -
Mechanism Of The Benzoin Condensation And Related Studies
(2014-09-22)Chapter 1: An assessment of the mechanism of the benzoin condensation. The reaction under non-hydroxylic conditions. The generally accepted mechanism for the well known benzion condensation is unviable for the following ... -
Mechanistic And Synthetic Investigations On Carboxylic Anhydrides And Their Analogs
(2011-02-09)This thesis reports diverse synthetic and mechanistic studies in six chapters, as summarized below. Chapter 1. Revised mechanism and improved methodology for the perkin condensation.1 The generally accepted mechanism for ... -
Metabolism Of Caffeine And Its Analogues By A Mixed Culture
(2012-02-24) -
A Mitsunobu-Michael Reaction Sequence to N-Heterocyclic Variants and Ti(III)-Mediated Synthesis of Terpenoids and N-Fused Indoles
The research work delineates a flexible and novel route for the diastereoselective construction of diversely substituted N-heterocyclic variants as valuable scaffolds for natural products and pharmaceuticals, starting from ... -
Modular Design Of Fluorescent Cation Sensors On A Bile Acid Scaffold
(2011-08-05)Bile acid-based cation sensors involving through space photo-induced electron transfer (PET) processes have been synthesized. In this approach, appropriate known fluorophores and aza crown ether receptor units were attached ... -
Molecular Construction Using Carbene and Diboron Systems: Catalytic Transformation of C-C and C-Hetero Atom Bonds
The thesis presents an unconventional approach for the molecular construction using carbenes as the carbon source, and water as the hydrogen source. A gold-catalyst has been used to transfer the carbenes to effect ... -
Molecular Expression Through Fluorescence: Studies In Probe Design And Aggregation
(2007-12-29)The present thesis entitled, "Molecular expression through fluorescence: Studies in probe design and aggregation" describes very simple bi-functional donor-acceptor poly-aromatic fluorophores that have been shown to possess ... -
Molecular Modulation Of Material Properties: Studies On Nanoparticles, Nanoassemblies, And Low Molecular-Mass Gelator
(2007-11-19)The present thesis titled “Molecular Modulation of Material Properties: Stud- ies on Nanoparticles, Nanoassemblies and Low Molecular Mass Gelator” deals with the preparation, characterization, and investigations into the ... -
N-Heterocyclic Carbene (NHC)-Catalyzed Stereoselective Synthesis of Six-Membered Heterocycles and Carbocycles
N-Heterocyclic carbene (NHC) based catalysis is employed for the generation of α,β-unsaturated acylazoliums followed by their interception with various nucleophiles, the formal [3+3] annulation reactions for the construction ...