Browsing Organic Chemistry (OC) by Title
Now showing items 158-177 of 427
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N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Dihydrothiopyranones, Functionalized Benzofurans and Extending Michael Acceptor Aldimine Umpolung
Carbenes exhibit high reactivity as divalent species with six electrons in their valence shell. Their electrophilic nature arises from an incomplete octet. However, when a heteroatom is introduced adjacent to the carbene ... -
N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of C-O Axially Chiral Diaryl Ethers, Tricyclic Lactones and Lactams
N-heterocyclic carbene (NHC)-catalyzed transformations with distinctive activation modes allow the facile synthesis of atropoisomers. In this context, we have demonstrated the NHC-catalyzed synthesis of axially chiral diaryl ... -
N-Heterocyclic Carbene-Catalyzed Synthesis of C–N Atropisomers and Heteroatom Chiral Molecules
Asymmetric catalysis has received worldwide interest due to the increasing demand for optically pure compounds in pharmaceuticals, agrochemicals, natural products, and materials science. Traditionally, research in this ... -
N-Heterocyclic Carbene-Catalyzed Synthesis of Oxazolones, e-Lactones and N-N Axially Chiral Molecules
The diverse reactivity of N-heterocyclic carbenes (NHCs) in organocatalysis is due to the possibility of different modes of action. Although NHC-bound enolates and dienolates were well-known, the NHC-bound cross-conjugated ... -
NanoPhotoCatalysis: A New Dimension in Synthetic Chemistry
Photocatalysis has emerged as a powerful tool in recent years to drive chemical transformations via electron/energy transfer, allowing access to several unstable or high energy intermediates. Thus, the design and ... -
Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins : Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond
(2017-12-03)This thesis titled, “Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins: Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond”, ... -
New Anthraquinone & Xanthone based Ligands as Potential Anti Cancer Agents via Selective Stabilization of G Quadruplex DNA and Theoretical Insights into G Quadruplex RNA Binding with Certain Small Molecules
In recent years, different small molecules have been synthesized for selective stabilization of G-quadruplex DNA structures over the most abundant double-stranded duplex DNA. Stabilization of G-quadruplex DNA by small ... -
New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production
(2018-05-10)The thesis entitled “New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production” encompasses design, computational calculations, and syntheses of diverse ... -
New methodologies for oxidation using peroxides mediated by Oxo-Chromium(VI) and Oxo-Boron(III) compounds
Part A: Oxidative Transformations with PDC/t-BuOOH Part A of this thesis focuses on oxidative transformations using the pyridinium dichromate (PDC)/tert-butyl hydroperoxide (t-BuOOH) reagent system. Chapter 1 describes a ... -
New methodologies for oxidation using peroxides mediated by Oxo-Chromium(VI) and Oxo-Boron(III) compounds
Hydrogen fluoride is one of the most inexpensive fluorinating reagents, used for fluorinations, but its use generally requires work under pressure due to its low boiling point. To overcome this difficulty, it has been found ... -
New Supramolecular Ion Sensing Probes And Their Application In The Detection Of Environmentally Relevant Ions
(2016-03-04)The thesis entitled “New Supramolecular Ion Sensing Probes and their Application in the Detection of Environmentally Relevant Ions” deals with the design and synthesis of several small molecular probes which can specifically ... -
Norbornyl System Revisited : Exploring A Versatile Building Block For The Syntheses Of Natural Products And Analogues
(2009-03-11)Carbohydrates are ubiquitous and important biomolecules. Initially thought to be dull, energy storing moieties, the importance of carbohydrates and their conjugates, glycoproteins and glycopilids, in cellular communication ... -
Norrish type 1 Cleavage reactions of cyclobutanethiones and media
The thesis entitled "Norrish Type I ?-Cleavage Reactions of Cyclobutanethiones and Photochemical Studies in Micellar Media" has been divided into two parts. Part I deals with the strain-assisted ?-cleavage reactions of ... -
Novel Approaches For The Synthesis Of Amino Acids And Piperidines, Including Asymmetric Strategies
(2014-04-23)Chapter I deals with novel approaches for α-amino acids. This chapter has been divided into three sections. Section A describes the synthesis of α-amino acids via the Beckmann rearrangement of carboxyl-protected β-keto ... -
Novel Biologically Active Chalcogenides : Synthesis And Applications
(2009-08-11)The thesis is divided in to five chapters. Chapter I: Synthesis of New thiolevomannosan derivatives In this chapter, a general and efficient method for the synthesis of conformationally locked thiosugars has been ... -
Novel Cationic Gemini Lipids, Click Chemistry Based Adducts And Amphiphile-Capped Silver Nanostructures : Synthesis, Aggregation And Biological Properties
(2013-01-23)The thesis entitled “Novel Cationic Gemini Lipids, Click Chemistry Based Adducts and Amphiphile-Capped Silver Nanostructures: Synthesis, Aggregation and Biological Properties” elucidates the design, synthesis, aggregation ... -
Novel Distamycin Frameworks For Enhancement And Photoregulation Of DNA Binding And Stabilization Of Higher Order DNA Structures
(2010-10-04)The thesis entitled “Novel Distamycin Frameworks for Enhancement and Photoregulation of DNA binding and Stabilization of Higher Order DNA Structures” has been divided into 4 chapters. Chapter 1 reviews the current trends ... -
Novel Redox Responsive Cationic Lipids, Lipopolymers, Glycolipids And Phospholipid-Cationic Lipid Mixtures : Syntheses, Aggregation And Gene Transfection Properties
(2018-01-07)The thesis entitled “Novel Redox Responsive Cationic Lipids, Lipopolymers, Glycolipids and Phospholipid-Cationic Lipid Mixtures: Syntheses, Aggregation and Gene Transfection Properties” elucidates the design, ...