Browsing Organic Chemistry (OC) by Title
Now showing items 146-165 of 416
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Microbiological transformations of terpenes and steroids
The thesis entitled “Microbiological Transformations of Terpenes and Steroids” is divided into three chapters. Chapter I — Microbiological Transformations of Monoterpenes This chapter opens by emphasizing microbiology as ... -
A Mitsunobu-Michael Reaction Sequence to N-Heterocyclic Variants and Ti(III)-Mediated Synthesis of Terpenoids and N-Fused Indoles
The research work delineates a flexible and novel route for the diastereoselective construction of diversely substituted N-heterocyclic variants as valuable scaffolds for natural products and pharmaceuticals, starting from ... -
Modification of photochemical reactivity by incorporation of organic molecules in organised media and photocycloaddition reactions ....
The thesis entitled (i) "Modification of Photochemical Reactivity by Incorporation of Organic Molecules in Organised Media" (ii) "Photocycloaddition Reactions of Thiocoumarin" consists of five chapters. Chapter 1 provides ... -
Modular Design Of Fluorescent Cation Sensors On A Bile Acid Scaffold
(2011-08-05)Bile acid-based cation sensors involving through space photo-induced electron transfer (PET) processes have been synthesized. In this approach, appropriate known fluorophores and aza crown ether receptor units were attached ... -
Molecular Construction Using Carbene and Diboron Systems: Catalytic Transformation of C-C and C-Hetero Atom Bonds
The thesis presents an unconventional approach for the molecular construction using carbenes as the carbon source, and water as the hydrogen source. A gold-catalyst has been used to transfer the carbenes to effect ... -
Molecular Expression Through Fluorescence: Studies In Probe Design And Aggregation
(2007-12-29)The present thesis entitled, "Molecular expression through fluorescence: Studies in probe design and aggregation" describes very simple bi-functional donor-acceptor poly-aromatic fluorophores that have been shown to possess ... -
Molecular Modulation Of Material Properties: Studies On Nanoparticles, Nanoassemblies, And Low Molecular-Mass Gelator
(2007-11-19)The present thesis titled “Molecular Modulation of Material Properties: Stud- ies on Nanoparticles, Nanoassemblies and Low Molecular Mass Gelator” deals with the preparation, characterization, and investigations into the ... -
N-Heterocyclic Carbene (NHC)-Catalyzed Stereoselective Synthesis of Six-Membered Heterocycles and Carbocycles
N-Heterocyclic carbene (NHC) based catalysis is employed for the generation of α,β-unsaturated acylazoliums followed by their interception with various nucleophiles, the formal [3+3] annulation reactions for the construction ... -
N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of Dihydrothiopyranones, Functionalized Benzofurans and Extending Michael Acceptor Aldimine Umpolung
Carbenes exhibit high reactivity as divalent species with six electrons in their valence shell. Their electrophilic nature arises from an incomplete octet. However, when a heteroatom is introduced adjacent to the carbene ... -
N-Heterocyclic Carbene-Catalyzed Enantioselective Synthesis of C-O Axially Chiral Diaryl Ethers, Tricyclic Lactones and Lactams
N-heterocyclic carbene (NHC)-catalyzed transformations with distinctive activation modes allow the facile synthesis of atropoisomers. In this context, we have demonstrated the NHC-catalyzed synthesis of axially chiral diaryl ... -
N-Heterocyclic Carbene-Catalyzed Synthesis of C–N Atropisomers and Heteroatom Chiral Molecules
Asymmetric catalysis has received worldwide interest due to the increasing demand for optically pure compounds in pharmaceuticals, agrochemicals, natural products, and materials science. Traditionally, research in this ... -
N-Heterocyclic Carbene-Catalyzed Synthesis of Oxazolones, e-Lactones and N-N Axially Chiral Molecules
The diverse reactivity of N-heterocyclic carbenes (NHCs) in organocatalysis is due to the possibility of different modes of action. Although NHC-bound enolates and dienolates were well-known, the NHC-bound cross-conjugated ... -
NanoPhotoCatalysis: A New Dimension in Synthetic Chemistry
Photocatalysis has emerged as a powerful tool in recent years to drive chemical transformations via electron/energy transfer, allowing access to several unstable or high energy intermediates. Thus, the design and ... -
Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins : Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond
(2017-12-03)This thesis titled, “Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins: Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond”, ... -
New Anthraquinone & Xanthone based Ligands as Potential Anti Cancer Agents via Selective Stabilization of G Quadruplex DNA and Theoretical Insights into G Quadruplex RNA Binding with Certain Small Molecules
In recent years, different small molecules have been synthesized for selective stabilization of G-quadruplex DNA structures over the most abundant double-stranded duplex DNA. Stabilization of G-quadruplex DNA by small ... -
New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production
(2018-05-10)The thesis entitled “New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production” encompasses design, computational calculations, and syntheses of diverse ... -
New methodologies for oxidation using peroxides mediated by Oxo-Chromium(VI) and Oxo-Boron(III) compounds
Part A: Oxidative Transformations with PDC/t-BuOOH Part A of this thesis focuses on oxidative transformations using the pyridinium dichromate (PDC)/tert-butyl hydroperoxide (t-BuOOH) reagent system. Chapter 1 describes a ... -
New methodologies for oxidation using peroxides mediated by Oxo-Chromium(VI) and Oxo-Boron(III) compounds
Hydrogen fluoride is one of the most inexpensive fluorinating reagents, used for fluorinations, but its use generally requires work under pressure due to its low boiling point. To overcome this difficulty, it has been found ...