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Controlling Conformation of Macromolecules by Immiscibility Driven Self-Segregation
(2018-05-09)
Controlling conformation of macromolecules, both in solution and solid state, has remained an exciting challenge till date as it confronts the entropy driven random coil conformation. Folded forms of biomacromolecules, ...
Nanoparticle Mediated Suppression of Protein Aggregation
(2018-05-11)
The increasing demands for biopharmaceuticals to treat different diseases have raised concerns about controlling the quality and efficacy of such pharmaceuticals. The design and formulation of a stable protein or peptide ...
Theoretical Studies of Energy Transport in Complex Systems
(2018-05-09)
Photosynthesis involves the absorption of photons by light-harvesting pigments and the subsequent transfer of excitation from the absorption centre to the reaction centre. This highly efficient phenomenon of excitation ...
First Hyperpolarizability (β) of Organic and Inorganic Compounds : Keto-Enol Tautomerism and Halogen Effect
(2018-05-09)
The work presented in this thesis has broadly established a few findings about the structure¬hyperpolarizability relation in molecular compounds: First, by measuring βHRS of an organic keto-enol tautomer, benzoylacetanilide ...
Design and Syntheses of Triarylborane Decorated Luminescent Dyes : Intriguing Optical Properties and Anion Sensing Applications
(2018-05-08)
The main thrust of this thesis is the development of new triarylborane containing luminescent molecules as well as utilizing triarylboron center as a receptor for the selective detection of biologically, environmentally ...
Synthetic Antioxidants : Structure-Activity Correlation Studies Of Glutathione Peroxidase Mimics And Peroxynitrite Scavengers
(2011-01-11)
Reactive oxygen species (ROS) such as superoxide radical anion (O2•¯), hydroxylradical (OH•), hydrogen peroxide (H2O2) and peroxynitrite (ONOO-) that are produced during the metabolism of oxygen under oxidative stress in ...
Metallo-β-Lactamase, Phosphotriesterase And Their Functional Mimics
(2011-01-11)
Metallohydrolases with dinuclear-zinc active sites perform many important biological hydrolytic reactions on a variety of substrates. In this regard, metallo-β-lactamases (mβ1, class B) represent a unique subset of zine ...
Modelling Stochasticity In Selected Biological Processes
(2010-08-16)
Biological processes at the cellular level take place in heterogeneous environments, and usually involve only a small number of molecules. They tend to exhibit strong time dependent fluctuations, as a result, and are, ...
Reductive And Metathetic Coupling Reactions Mediated By Group (IV) Metal Alkoxides
(2010-10-19)
Several organic transformations are mediated by group(IV) metal alkoxides. The reactivity is based on the basic nature of alkoxide group, Lewis acidic nature of the group(IV) metals, insertion of unsaturated molecules into ...
Studies Of MnO2 As Active Material For Electrochemical Supercapacitors
(2010-11-02)
Electrical double-layer formed at the interface between an electrode and an electrolyte has been a topic of innumerable studies. The electrical interface plays a crucial role in kinetics, mechanisms and applications in ...