etd AT Indian Institute of Science: Recent submissions
Now showing items 121-140 of 6565
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On regular subalgebras of symmetrizable Kac-Moody algebras and related combinatorics
In this thesis, we study two aspects of Kac-Moody algebras. One is to understand the subalgebras that can be embedded inside a Kac-Moody algebra as subalgebras generated by real root vectors. The other one is to explicitly ... -
Mixed Variational Approaches in Nonlinear Continuum Mechanics and Discretization by Finite Element Exterior Calculus
Numerical solution techniques for nonlinear elasticity have been an active area of research for a while. Right from the early days, it was recognized that constructing well-performing FE approximations for nonlinear ... -
Structural and functional characterization of human regulator of telomere elongation helicase 1 (RTEL1)
RTEL1 is an ATP-dependent DNA helicase that translocates on the single-stranded DNA (ssDNA) from 5′ to 3′ direction. It is an iron-sulfur (Fe-S) cluster and DEAH motif-containing helicase. RTEL1 has been shown to play ... -
Understanding the mechanism of host deacetylase SIRT1 and SIRT3 in the modulation of Salmonella pathogenesis
Host sirtuins are one of the important modulators of host immuno-metabolic regulation. However, the role of sirtuins in the modulation of the immune metabolism pertaining to Salmonellosis is largely unknown. Here, we ... -
Operationalising Sustainability in Smart Manufacturing Systems: A Model-Based Approach
This dissertation addresses the need for sustainability in manufacturing industries by leveraging digitalization and Model-Based Systems Engineering (MBSE). The research presents a comprehensive framework for operationalizing ... -
Multistability in cellular differentiation enabled by three and four node mutually repressive regulatory networks: A case study of CD4+ T-cell decision making
Cellular differentiation is controlled by the complex dynamics of gene regulatory networks (GRNs), often featuring multistability, where multiple stable states represent different phenotypes. A common example is the toggle ... -
Sequence Alignment to Cyclic Pangenome Graphs
The growing availability of genome sequences of several species, including humans, has created the opportunity to utilize multiple reference genomes for bioinformatics analyses and improve the accuracy of genome resequencing ... -
Modelling and evaluation of nitrate transit times in groundwater systems
Transit time distribution is one of the fundamental descriptors of flow and transport behavior of catchments. Intensification of agriculture and consequent anthropogenic inputs of nitrate rich fertilizers in agricultural ... -
Advancements in Microcantilever Sensor Technology: Gas Sensing Application
Micro and nanoelectromechanical systems (M&NEMS) have great potential in sensor technologies, which are used for detecting mass or gas, measuring force and acceleration, and in applications related to memory storage and ... -
Advanced Architectures for Cascaded Raman Fiber Lasers
Fiber lasers have exhibited significant expansion in their diverse applications within the fields of communications, industrial operations, defence, and the medical sector. They require a rare earth doped element as ... -
Design of Immunogens Derived from the Conserved Stem of Influenza Virus Hemagglutinin
Embargo up to 15/7/2025 -
Synthesis and Applications of Unusual Self-assembled Coordination Architectures
Biological systems like enzymes have complex structures which help in executing intricate chemical reactions. Endeavoring to replicate such chemical reactions, chemists have crafted discreate molecular structures ... -
Fabricating Physical and Robotic Systems to Investigate Collective Behavior
The motion of particles has always been fascinating for scientists. We, as scientists, try to decode the mysteries of motion of massive objects like black holes, stars, and planets to objects nearly void of mass such as ... -
Gallium Oxide Vertical Power Devices - Modeling, Material Growth, and Hetero-epitaxial Integration with Silicon
𝛽-Ga2O3 is a candidate for a new generation of power semiconductors that can significantly lower the conduction losses and increase power density in the power converters. PFOM or power figure of merit (V2Br/Ron) is a ratio ... -
Development of an Intraoperative Probe for Brain Tumour Delineation Combining Multimodal Tissue Characterization and Soft-Robotics
Accurate identification of surgical margins in brain tumors is of significant prognostic importance. Despite the availability of 5-ALA and image guidance methods, recognizing tumor boundaries is highly subjective, dependent ... -
Synergistic Exploration of Oxide Cathode Materials for Potassium-ion Batteries
Since their inception by Sony® in 1991, Li-ion batteries have become dominant in various energy storage applications. However, the ever-growing energy demand coupled with sparsely distributed lithium resources provide ... -
Data-Driven Approach to Estimate WCET for Real-Time Systems
Estimating Worst-Case Execution Time (WCET) is paramount for developing Real-Time and Em- bedded systems. The operating system’s scheduler uses the estimated WCET to schedule each task of these systems before the assigned ... -
Phosphate-based Mixed Polyanionic Positive Insertion Materials for Energy Storage Applications
Mixed polyanionic insertion materials offer a rich treasure house to develop robust cathode insertion materials having a desirable combination of chemical and thermal stability, as well as tuneable redox voltage and ... -
Experimental, Numerical and Probabilistic Analysis of Reinforced Anchors for Transmission Tower Foundations
The foundations of tall structures such as transmission towers are subjected to loads in three directions coming from wind and other environmental events. The use of anchors for application in transmission tower foundations ... -
Barrier Function Inspired Reward Shaping in Reinforcement Learning
Reinforcement Learning (RL) has progressed from simple control tasks to complex real-world challenges with large state spaces. During initial iterations of training in most Reinforcement Learning (RL) algorithms, agents ...