etd AT Indian Institute of Science: Recent submissions
Now showing items 101-120 of 6420
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Graph Clustering Approaches for Speaker Diarization of Conversational Speech
In this era of advanced machine intelligence, real-world speech applications need to be equipped to deal with conversations involving multiple speakers. An essential first step in speech information extraction from ... -
Studies on Iron(III) Complexes for Cellular Imaging and Targeted Photodynamic Therapy
Cancer is caused by uncontrolled division of abnormal cells. Surgery, chemotherapy, and radiation therapy are most widely used for its treatment. However, due to serious limitations of these traditional treatment modalities, ... -
Elucidating the Role of miR-617 in Oral Squamous Cell Carcinoma Pathogenesis
Oral Squamous Cell Carcinoma (OSCC) or oral cancer is the malignancy of the epithelial lining of the oral cavity. It is the leading cause of cancer-related mortality in Indian males and despite technological advancements, ... -
Design and Performance Analyses of Osculating Cone Waveriders
Modern mission requirements for long-range maneuverable hypersonic vehicles for space, military, and transportation applications necessitate vehicle design innovations. The primary challenges that a hypersonic vehicle ... -
Growth and Characterization of Single crystalline VO2 Heterostructures
Vanadium dioxide is a strongly correlated material with a temperature driven metal-to-insulator transition (MIT) near room temperature (~340 K). This electronic transition is accompanied by a structural transition from ... -
From Impact to Encapsulation: Advancing Droplet Technologies with Liquid Marbles
Droplets, in their myriad forms and functions, have become indispensable players in the world of microreactors, drug delivery systems, crystallization studies, and cell culture platforms. These tiny, self-contained units ... -
Evaluation Frameworks for Informed Multi-Site Multi-Variate Hydrological Assessment
The process of choosing a suitable hydrological model, calibrating it, and evaluating its performance poses intricate challenges for a modeler. The process of model selection is frequently influenced by the modeller's ... -
Novel Microfluidic Tools for Multiplex Colorimetric Detection of Analytes and Point Mutation Detection in Infectious Pathogens
Recently, the need for affordable point-of-care tests has grown exponentially. An ideal point of care (POC) test or device should satisfy the WHO-endorsed ASSURED criteria, meaning that the test/device should be accessible, ... -
Extratropical Influence on the Sub-seasonal Rainfall Deficit in Indian Summer Monsoon
The variability of Indian monsoon on a range of timescales - seasonal to interannual to decadal - has been studied and characterised extensively over the past several decades. On the mechanistic front, the role ... -
Analysis of Fetal Heart Sound for Fetal Heart Rate Monitoring
Perinatal mortality is the number of stillbirths and deaths during the first seven days of life per 1000 live births. Most (98%) of this death occurs in low- and middle-income countries (LMIC) and is known as the 'silent' ... -
Investigating mechanisms underlying astrocytic involvement in depressive-like behavior and antidepressant action
Major Depressive disorder (MDD) is a complex, multifactorial psychiatric illness which affects over 20% of the population worldwide. Despite its prevalence, our understanding of its pathophysiology is severely limited, ... -
A Framework for Effectiveness-based Sustainability Assessment in Manufacturing – A Product Life Cycle Approach
In recent decades, various human health impacts and environmental concerns (e.g., microplastic pollution, chemical exposure, biodiversity loss) associated with manufacturing/product life cycles have surfaced, threatening ... -
Investigations of Sensors Based on New Molecular Architectonics: Synthesis, Fabrication and Application
Rapid industrialization and expansion of urban landscapes in large cities generate maximum polluting ingredients to the surrounding environment. While organic contaminants are naturally occurring, the increase in human ... -
Synthesis of Monodispersed Pdms Microspheres of Tunable Modulus Using Droplet Microfluidics and Study of the Rheology of Dense Suspensions of Rigid and Soft Particles in Shear Flow
We report the synthesis of monodispersed PDMS microspheres of tuneable modulus using a droplet-based microfluidics approach. Nevertheless, polymer microspheres can be used as a model representative particle to mimic the ... -
Modelling Approaches for Planning Renewable Energy Transitions and Integrating Demand-Side Interventions in Electricity Systems
As global awareness of the devastating impacts of climate change is growing, nations are uniting to address the imperative of decarbonization. The electricity sector, known for its high carbon intensity, accounts for the ... -
Vorticity and scalar transport in turbulent round jets with and without heating
The round turbulent jets are ubiquitous in both natural and engineered systems such as clouds, engine exhausts, chimney plumes, and respiratory flows. We aimed to understand the vorticity and scalar transport in turbulent ... -
Intense Rainfall Events over the West Coast of India
West coast of the Indian peninsula is one of the regions which receive very heavy rainfall during the summer monsoon season. Average June-September rainfall over the parts of coastal Karnataka, Konkan and Goa exceed 250 ... -
Effect of Electric Current Pulses on Pre-cracked Thin Metallic Conductors: From Crack Propagation to Healing of Cracks
Both scientifically and technologically, it is important to investigate the effects of electric current on the structural integrity of metallic components. As an electric current reverses its direction across a crack, ... -
Solution NMR studies of a potent subtilisin inhibitor from Budgett’s frog and the catalytic subunit of AHAS
This thesis involves a detailed structural study of two molecular systems, a small disulfide-rich peptide LL-TIL and a large catalytic subunit of AHAS. Subtilisin inhibitors play an important role in fighting against ... -
Understanding structure, function, and dynamics in macromolecular complexes
In the scope of my thesis work, a concerted effort was undertaken to elucidate bi- ological functions through the lens of structural analysis, employing protein dy- namics. The role of protein dynamics in shaping and ...