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    Engineering Reverse Turns: Implications in Conformation, Stability and Bioactivity of Peptides and Proteins 

    Lahiri, Priyanka
    The work presented in this thesis provides an overview of the potential role of N-methylation in inducing reverse turns. Backbone N-methylation is one of the common modifications designed by nature and exploited by humans ...

    NMR Structural Studies on the Harmonin-N-like Domain 2 of Human RTEL1 

    Basak, Sanmoyee

    Molecular Characterization of Mannose Binding Lectins 

    Nisha, G J
    Lectins are proteins of non-immunologic origin that bind to carbohydrates with high fidelity. They constitute a large class of multivalent recognition molecules that specifically interact with their cognate sugar moieties ...

    Structure analysis of lectin and lectin-like domains from Entamoeba histolytica 

    Khan, Farha
    Lectins are a diverse group of proteins which can recognize different types of carbohydrates specifically and reversibly. Though first characterized in plants, lectins have now been identified in all other forms of life. ...

    Scanning mutagenesis studies of HIV-1 Env immunogenicity and structure 

    Datta, Rohini
    Human Immunodeficiency Virus type 1 (HIV-1) is the etiological agent of Acquired Immunodeficiency Syndrome (AIDS). AIDS is a global pandemic with 36.7 million people living with HIV-1 all over the world and approximately ...

    Design, Synthesis, and Bioactivity of Thioamidated Macrocyclic Peptides 

    Verma, Hitesh
    The work presented in this thesis describes the comprehensive study related to thioamidated macrocyclic peptides. We study the underexplored class of peptide bond isostere; thioamides in the context of small macrocyclic ...

    Small Heat Shock Proteins from Bacteria and a Bacteriophage 

    Biswas, Sreeparna
    Proteins can unfold during heat and other types of stress and tend to aggregate with subsequent loss of function. This event is prevented by small Heat Shock Proteins (sHSPs) acting as molecular chaperones. sHSPs do not ...

    Crystallographic and analytical ultracentrifugation studies of the E. coli acetohydroxy acid synthase I enzyme 

    Bansal, Akanksha
    This thesis ellucidates the mechanism of activation and regulation of AHAS I enzyme from Escherichia coli that was characterised using crystallographic and sedimentation velocity analytical ultracentrifugation studies. AHAS ...

    Understanding intramolecular signal transduction in regulated proteases of the High Temperature Requirement A family 

    Gupta, Arvind Kumar
    Protein homeostasis in all organisms is a complex process involving regulatory mechanisms that govern protein synthesis, post-translational events and degradation. The protein degradation mechanism serves multiple functions ...

    Resource allocation during Flavivirus lifecycle 

    Rizvi, Syed Vaseef Ul Asghar
    Single-stranded RNA virus infection cycle progresses by resource (viral RNA) allocation to segregated macromolecular complexes: host ribosomes (translation), viral RNA polymerase (replication) and viral structural proteins ...
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    AuthorAhmed, Tanzeel (1)Athreya, Arunabh (1)Bajaj, Priyanka (1)Bandopadhyay, Devleena (1)Banerjee, Sunaina (1)Bansal, Akanksha (1)Baratam, Krishnakanth (1)Basak, Sanmoyee (1)Basu Roy, Tanaya (1)Behera, Debashree (1)... View MoreSubject
    NATURAL SCIENCES (80)
    E coli (7)Bacteria (6)Mycobacterium tuberculosis (5)Structural Biology (5)Cryo-EM (4)Toxin-antitoxin (4)Biophysics (3)Deep mutational scanning (3)Human Immunodeficiency Virus (3)... View MoreHas File(s)Yes (76)No (4)

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