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Intrinsic Versus Induced Variations In DNA Structure
(2011-07-18)
The binding of different proteins involved in processes such as transcription, replication and chromatin compaction to regions of the genome is regulated by the structure of DNA. Thus, DNA structure acts as the crucial ...
Studies On Sesbania Mosaic Virus Asssembly And Structure And Function Of A Survival Protein (SurE) From Salmonella Typhimurium
(2011-03-29)
X-ray crystallography is a powerful method for determining the three-dimensional structures of biological macromolecules at atomic resolution. Crystallography can reliably provide the answer to many structure related ...
Structural And Functional Studies On Staphylococcus Aureus Enzymes Involved In L-Lysine Biosynthesis
(2011-05-24)
Proteins associated with metabolic pathways have received considerable attention in an effort to understand the molecular details of the complex reactions catalyzed in vivo. Enzymes belonging to these pathways have also ...
Design and Stabilization of Stem Derived Immunogens from HA of Influenza A Viruses
(2018-07-19)
Influenza virus belongs to the Orthomyxovirus family of viruses that causes respiratory infection in humans, leading to morbidity and mortality. The mature influenza A virion has an envelope that contains two major surface ...
Exploring Protein-Nucleic Acid Interactions Using Graph And Network Approaches
(2009-09-22)
The flow of genetic information from genes to proteins is mediated through proteins which interact with the nucleic acids at several stages to successfully transmit the information from the nucleus to the cell cytoplasm. ...
Aromatic Interactions In Peptides : Designed Helices And β-Hairpins
(2009-04-15)
Design of complex protein folds requires complete understanding of the stereochemical principles that govern polypeptide chain folding. Extensive studies on design and synthesis of specific secondary structures like ...
Structural and Functional Studies on Pyridoxal Kinase and Pyridoxal 5′-phosphate Dependent Enzymes
(2018-07-04)
Most of the chemical reactions of living cells are catalyzed by protein enzymes. These enzymes are very efficient and display a high degree of specificity with respect to the reaction catalyzed. Cellular activities depend ...