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Structure-Function Studies On Triosephoshate Isomerase From Plasmodium falciparum And Methanocaldococcus jannaschii
(2010-08-16)
This thesis describes studies directed towards understanding structure-function relationships of triosephosphate isomerase (TIM), from a protozoan parasite Plasmodium falciparum and a thermophilic archaea Methanocaldococcus ...
Newer Insights On Structure, Function And Regulation Of Dps Protein From Mycobacterium smegmatis
(2010-12-29)
The first chapter will provide an introduction to the physiology, pathogenesis and biology of mycobacteria. Host-pathogen interactions, different modes of resistance of the bacteria, adaptations for survival under nutrient ...
Epileptiform Activity Induced Alterations In Ca2+ Dynamics And Network Physiology Of Hippocampal Neurons - In Vitro Studies
(2010-07-15)
Epilepsy is characterized by the hyperexcitability of individual neurons and hyper synchronization of groups of neurons (networks). The acquired changes that take place at molecular, cellular and network levels are important ...
Unusual Acylation Properties Of Type II Fatty Acid Biosynthesis Acyl Carrier Proteins
(2010-07-06)
This thesis entitled ‘ Unusual Acylation Properties of Type II Fatty Acid Biosynthesis Acyl Carrier Proteins’ describes the discovery of self-acylation and malonyl transferase activity in acyl carrier proteins involved in ...
Computer Modeling and Molecular Dynamics Simulation Of Angiogenins And Its Ligand Bound Complexes
(Indian Institute of Science, 2006-05-04)
Computational structural biology
Even with rapid advances in structure determination methods, there is a long gap to be bridged between the number of proteins that have been sequenced and the number whose three-dimensional ...
Orienting Macromolecule At The Air - Water Interface : DNA-Protein Interaction On Langmuir Films
(2010-07-23)
The Langmuir – Blodgett (LB) technique is about forming insoluble monolayer on the surface of aqueous solution and recently, it has emerged as one of the best method to study floating monolayer at the air – water interface. ...
Mass Spectrometric Sequencing Of Acyclic And Cyclic Peptides
(2009-05-18)
Elucidation of the primary structure of peptides and proteins de novo by mass spectrometry (MS) has become possible with the advent of tandem MS methods. The most widely used chemical method due to Edman (Edman & Begg, ...
In Silico Perspectives on RNA Structures Modulating Viral Gene Expression and Mechanics of tRNA Transport
(2018-07-19)
The repertoire of cellular functions mediated by Ribonucleic acid (RNA) molecules have expanded considerably during the last two decades. The role played by RNA in controlling and regulating gene expression in ...
Solution NMR Studies Of E.Coli Acetohydroxy Acid Synthase (AHAS) I
(2010-04-13)
Branched chain amino acids are classified as essential amino acids since their biosynthetic routes or pathways are restricted only to micro-organisms, fungi and plants. Given their unique distribution, the enzymes of the ...
Thermodynamic Characterization Of Wild Type And Mutants Of The E.coli Periplasmic Binding Proteins LBP, LIVBP, MBP And RBP
(2009-03-13)
Native states of globular proteins typically show stabilization in the range of 5 to
15 kcal/mol with respect to their unfolded states. There has been a considerable progress in the area of protein stability and folding ...