Browsing Molecular Biophysics Unit (MBU) by Subject "Computational Biology"
Now showing items 1-3 of 3
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Integration of sequences, structures, dynamics to study functional divergence in homologous proteins and their assemblies
Functions of proteins are governed by their sequences, structures, dynamics and assembly. Modulation of these factors during evolution renders functional divergence in related proteins that have originated from the common ... -
Stereochemical studies on peptide and protein structures: Implications for validation, flexibility, and dynamics
Accuracy of 3-D structures of proteins is crucial, both in terms of its agreement with the experimental data used to determine the structure and stereochemistry, especially when they are utilized for applications like drug ... -
Structural Feature of Prokaryotic Promoters and their Role in Gene Expression
(2018-05-14)Transcription initiation is an important step in the process of gene regulation in prokaryotes. Promoters are stretches of DNA sequence that are present in the upstream region of transcription start sites (TSSs), where RNA ...