ISWI (Imitation Switch) family of chromatin remodeling complexes mobilize nucleosomes to control DNA accessibility, which manages various DNA template-associated processes like replication, transcription, and repair. ...

Gliomas are tumors of the central nervous system arising from glial cells. Based on the origin of the cell type, it can be astrocytoma, oligodendroglioma, and ependymoma. Astrocytoma is the most common type of glioma, ...

Glioblastoma (GBM) is an aggressive form of adult brain tumors. The current standard of care includes maximal safe resection followed by concurrent chemo-radiation therapy and adjuvant chemotherapy with temozolomide. ...

G protein–coupled receptors (GPCRs) represent the largest family of membrane receptors and are key regulators of cellular signaling. While extensively targeted in various diseases, their potential in oncology especially ...