Browsing Microbiology and Cell Biology (MCB) by Subject "Sirtuins"

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    • ROLE OF SIRT6 AND PARP-1 IN MUSCLE HOMEOSTASIS 

      Mishra, Sneha
      Sirtuins and PARPs are stress responsive family of proteins regulating genome instability, inflammation, aging-related diseases and energy metabolism. Both sirtuins and PARPs are NAD+ enzymes with deacetylase and ADP-ribose ...

    • Role of SIRT6 in Myofibroblast Cell Death 

      Subramanian, Veena (2018-01-10)
      Cardiovascular diseases are one of the leading causes of mortality. A common denominator across most of the cardiovascular diseases like diabetic cardiomyopathy, hypertrophic cardiomyopathy, myocardial infarction and dilated ...

    • Understanding the Role of SIRT2 in Cardiac Hypertrophy, Cell Death and Glucose Homeostasis 

      Sarikhani, Mohsen
      Over the last century the major causes of human deaths and ailments has shifted from acute infectious diseases to chronic aging related disorders like cancer and type-2 diabetes. The aging process is a universal property ...