Animal models play a crucial role in helping neuroscientists unravel the computations supporting behaviour at the resolution of a single neuron in the brain. In vision science, the macaque monkey is the pre-eminent model ...

In everyday life we make a variety of reaching movements. Most of these reaching movements have a clear objective of bringing the hand to the spatial location of the object of interest. Although we typically do not explicitly ...

Autism Spectrum Disorders (ASD) constitutes a spectrum of developmental disorders that share common phenotypes of social and communication deficits and repetitive behaviours. ASDs have many possible underlying causes ...

Humans and other animals form internal mental maps of the outer world in order to navigate. Hippocampal place cells and grid cells in MEC (medial entorhinal cortex) are the key components of this navigation system. However, ...

Amyloid Precursor Protein (APP) is a key player in Alzheimer’s disease (AD). Despite intuitive insights into differential proteolysis of APP, there is a little understanding of how the amyloidogenic machinery is distributed ...

Gaze or eye-head coordination is an ethologically and physiologically important process that directs the visual system to objects of interest. Due to its relative simplicity, it is an ideal system to study multi-effector ...

Vision is computationally challenging because objects in the real world can change in size, position, viewpoint etc., and therefore cast a myriad images on the retina. Viewpoint changes are particularly challenging because ...

Synapse is the fundamental unit of synaptic transmission. Learning, memory and neurodegenerative diseases of the brain are attributed to the maintenance and alteration in synaptic connections. The efficiency for synaptic ...

Cerebella granule neuron progenitors (CGNPs) give rise to a homogenous group of neurons called the cerebellar granule neurons in the developing cerebellum (a hindbrain structure classically associated with fine motor ...

Alzheimer’s disease is a debilitating, progressive neurodegenerative disorder in the elderly, characterized by severe loss of memory and higher cognitive functions. In the hundred years since its discovery, Alzheimer’s ...