| dc.contributor.advisor | Somasundaram, Kumaravel | |
| dc.contributor.author | Arora, Anjali | |
| dc.date.accessioned | 2021-09-23T06:46:15Z | |
| dc.date.available | 2021-09-23T06:46:15Z | |
| dc.date.submitted | 2018 | |
| dc.identifier.uri | https://etd.iisc.ac.in/handle/2005/5339 | |
| dc.description.abstract | Glioblastoma (GBM) is an aggressive form of adult brain tumors. The current standard of care
includes maximal safe resection followed by concurrent chemo-radiation therapy and adjuvant
chemotherapy with temozolomide. Despite advances in biology and treatment modalities, the
prognosis of GBM remains poor. The research in the field of GBM management includes
finding factors which can be utilized to improve diagnosis and prognosis, also to reduce
chemoresistance. Utilizing proteomics and genomics approaches we investigated the role of
biomarkers, tumor microenvironment and factors responsible for chemoresistance | en_US |
| dc.language.iso | en_US | en_US |
| dc.relation.ispartofseries | ;G29329 | |
| dc.rights | I grant Indian Institute of Science the right to archive and to make available my thesis or dissertation in whole or in part in all forms of media, now hereafter known. I retain all proprietary rights, such as patent rights. I also retain the right to use in future works (such as articles or books) all or part
of this thesis or dissertation | en_US |
| dc.subject | Glioblastoma | en_US |
| dc.subject | chemotherapy | en_US |
| dc.subject | biomarkers | en_US |
| dc.subject | chemoresistance | en_US |
| dc.subject | ESTIMATE | en_US |
| dc.subject.classification | Research Subject Categories::NATURAL SCIENCES::Biology::Cell and molecular biology | en_US |
| dc.title | Improving Glioblastoma Management: A Study of Biomarkers, Tumor Microenvironment and Chemoresistance | en_US |
| dc.type | Thesis | en_US |
| dc.degree.name | PhD | en_US |
| dc.degree.level | Doctoral | en_US |
| dc.degree.grantor | Indian Institute of Science | en_US |
| dc.degree.discipline | Faculty of Science | en_US |
