Site-selective C-H Functionalization using Directing Group Strategy via C-H Bond Activation
dc.contributor.advisor | Prabhu, K R | |
dc.contributor.author | Bettadapur, Kiran R | |
dc.date.accessioned | 2018-11-06T09:44:39Z | |
dc.date.available | 2018-11-06T09:44:39Z | |
dc.date.submitted | 2017 | |
dc.identifier.uri | https://etd.iisc.ac.in/handle/2005/4134 | |
dc.description.abstract | The thesis entitled “Site-selective C-H Functionalization using Directing Group Strategy via C-H Bond Activation” is divided into two sections. Section A, is presented in four chapters, comprising the work on the aromatic ortho-C-H addition to maleimide, mechanistic studies with DFT, ortho-C-H oxidative Heck reaction with maleimides, and ortho-C-H addition to maleimide with a deciduous/traceless directing group. Section B describes a formal oxidative [2+2+2] benzannulation of indoles with alkynes via a directing group strategy. Publications: 1. Ru (II)-Catalyzed C–H Activation: Ketone-Directed Novel 1, 4-Addition of Ortho C–H Bond to Maleimides KR Bettadapur, V Lanke, KR Prabhu; Org. Lett., 2015, 17, 4658-4661 2. A Deciduous Directing Group Approach for the Addition of Aryl and Vinyl nucleophiles to Maleimides KR Bettadapur, V Lanke, KR Prabhu; Chem. Comm., 2017, 53, 6251-6254 3. Weak Directing Group Steered Formal [2+2+2]- Oxidative Cycloaddition for Selective Benzannulation of Indoles KR Bettadapur, R Kapanaiah, V Lanke and KR Prabhu; J. Org. Chem., DOI: 10.1021/acs.joc.7b02719 | en_US |
dc.language.iso | en_US | en_US |
dc.relation.ispartofseries | G28634; | |
dc.rights | I grant Indian Institute of Science the right to archive and to make available my thesis or dissertation in whole or in part in all forms of media, now hereafter known. I retain all proprietary rights, such as patent rights. I also retain the right to use in future works (such as articles or books) all or part of this thesis or dissertation | en_US |
dc.subject | C-H Bond Activation | en_US |
dc.subject | C-H Functionalization | en_US |
dc.subject | Maleimides | en_US |
dc.subject | C–H Bond - Maleimides | en_US |
dc.subject | Rh(III)-Catalyzed C-H Activation | en_US |
dc.subject | Indoles | en_US |
dc.subject | Maleimide | en_US |
dc.subject | Indole | en_US |
dc.subject.classification | Organic Chemistry | en_US |
dc.title | Site-selective C-H Functionalization using Directing Group Strategy via C-H Bond Activation | en_US |
dc.type | Thesis | en_US |
dc.degree.name | PhD | en_US |
dc.degree.level | Doctoral | en_US |
dc.degree.grantor | Indian Institute of Science | en_US |
dc.degree.discipline | Faculty of Science | en_US |
Files in this item
This item appears in the following Collection(s)
-
Organic Chemistry (OC) [214]