Chemical Engineering (CE): Recent submissions
Now showing items 21-40 of 138
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Paper microfluidic tools to improve the sensitivity and dynamic range of point-of-care immunoassays
Over the past decade, developing affordable home-based tests to diagnose infectious diseases has become a pressing need. The lateral flow immunoassay (LFIA) is the most successfully commercialized point-of-care immunoassay. ... -
Investigating Membrane Dynamics And Oligomerization Of Pore-forming Toxins Using Single-molecule Fluorescence Techniques
The biological membrane is a thin fluidic matrix composed of a lipid bilayer that forms the primary cellular barrier against the extracellular environment. The high-density of embedded proteins and glycosylated molecules ... -
Droplet Isothermal Amplification For Nucleic Acid Quantification
Nucleic acid quantification (NAQ) is extensively employed for gene expression analysis, monitoring viral loads, detecting rare or dysfunctional cells, and assessing treatment regimes. The gold standard, quantitative ... -
Dynamics and Rheology of Non-colloidal Suspensions: Active and Soft Deformable Particles
Classical works on the suspensions of rigid spherical and ellipsoidal particles have been carried out by Einstein and Jeffery. However, in nature and industry, we come across materials that are either deformable or active. ... -
Photocatalytic and Photoelectrocatalytic systems for water remediation and energy applications
This PhD work consists of two main parts. The first part focuses on photocatalytic systems for water remediation from bacteria and phenolic compounds, and the second part deals with photoelectrocatalytic systems for biomass ... -
Study of solvent induced polymorphism and crystal nucleation from solution
Crystal polymorphism is the existence of different crystal structures for the same compound. Different polymorphs will have different physical properties, such as solubility and dissolution rate. The early stage of ... -
Rheology of dense granular materials
Granular materials are frequently encountered in our daily lives and are widely used in several industrial processes. Characterising the flow of these materials has always proved challenging due to the lack of simple ... -
Development of noble metal catalysts and detailed kinetic models for CO oxidation and water gas shift reactions
Noble metal (Pt, Pd, Rh) based catalysts have been highly effective for CO abatement applications such as CO oxidation and the water gas shift reaction (WGS). In the venture for development of novel catalysts, noble metal ... -
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich membranes through atomistic molecular dynamics simulations. The PFT of interest is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ... -
Quality-quantity trade off during antibody production and the design of optimal passive immunization protocols
Passive immunization has been used classically to rapidly clear antigen and reduce disease burden. Surprisingly, recent studies have found passive immunization to induce lasting improvements in the humoral response, ... -
FLIPP-NAAT: A paper-based LAMP assay for point-of-care TB detection
Molecular diagnostic techniques like polymerase chain reaction (PCR) revolutionized the world of healthcare. Instead of waiting for infectious agents to physically grow as in conventional culture-based tests, genetic ... -
Molecular dynamics investigations of the bacterial cell envelope: Elucidating differential barriers for antimicrobials
The bacterial cell envelopes possess a complex multilayered architecture exhibiting unique properties evolved to regulate interactions with the external environment and molecules with antimicrobial properties. A molecular ... -
Flow and structure of dense granular materials
Granular materials are frequently encountered in our daily lives and are widely processed forms of matter in various industries. Despite decades of research, the mechanical behavior of granular materials is not well ... -
Droplet Microfluidics for Nucleic Acid Quantification and Single Cell Analysis
Droplet microfluidics provides controlled generation of monodispersed droplets of the order of a few picoliters in multiphase microfluidic systems. These droplets are employed as micro-reactors to conduct chemical/biochemical ... -
An Approach Towards Inactivation of Susceptible and Antibiotic Resistant Bacterial Contamination using Novel Photo–(electro)-catalysts
Water in most rivers in India does not meet the standards for drinking and even for bathing purposes due to the high concentration of coliforms, organic and inorganic contaminants. Overuse, uncontrolled release and careless ... -
Study of Phase Equilibria and Interfacial Properties of Systems Containing Clathrate Hydrates Using Molecular Simulations
Gas hydrates, also known as clathrate hydrates are nonstoichiometric and crystalline solids composed of water and gas molecules. If the gas molecules are natural gas components, such as methane, ethane, propane, etc., ... -
A framework for optimizing immunotherapy for long-term control of HIV
HIV infects around 1 million people every year. Antiretroviral therapy (ART) is used to suppress viral replication and control disease progression but it cannot eradicate the virus. ART is therefore lifelong. Today, e ... -
Syngas Production by Methane Reforming and H2 Purification by CO Abatement over Transition Metal-Substituted Reducible Oxides
Methane and carbon dioxide are two major greenhouse gases, with CH4 having higher potency towards global warming. Several methods have been explored for transforming CH4 into higher value products, of which syngas production ... -
Study of Solvent Induced Crystal Polymorphism via Molecular Simulations of Crystal Nucleation
The ability of a compound to exist in different crystal structures is called crystal polymorphism and such crystals of varied spatial arrangement are called polymorphs. The polymorphic forms can differ in their properties ... -
Rheology of Dense Granular Chute Flows
Granular flows have always fascinated researchers through its complex and mysterious behavior. Although a collection of solids, they exhibit properties like that of fluids. Flows over an inclined plane, known as chute flow, ...