Browsing Chemical Engineering (CE) by Subject "Research Subject Categories::TECHNOLOGY::Chemical engineering"
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Accurate Prediction of Enhancement Factors for Water Flow Through Boron Nitride Nanotubes
Water in nanoconfined spaces, such as nanotubes, exhibit anomalous yet intriguing behaviour compared to bulk water, a better understanding of which can enable us to realize a sustainable future. Nanotubes are atomically ... -
Advancements in Nucleic Acid Lateral Flow Assay
In recent decades, the demand for rapid and precise nucleic acid amplification tests (NAATs) has grown significantly, driven by the need to address pandemics like COVID-19 and diagnose infectious diseases such as ... -
Computational study of membrane driven secondary structural changes in proteins
Conformational changes in proteins, the most abundant biomolecule found in all living organisms, are ubiquitous and triggered by several factors essential for protein function. Protein conformational changes typically occur ... -
Development of noble metal catalysts and detailed kinetic models for CO oxidation and water gas shift reactions
Noble metal (Pt, Pd, Rh) based catalysts have been highly effective for CO abatement applications such as CO oxidation and the water gas shift reaction (WGS). In the venture for development of novel catalysts, noble metal ... -
Droplet Isothermal Amplification For Nucleic Acid Quantification
Nucleic acid quantification (NAQ) is extensively employed for gene expression analysis, monitoring viral loads, detecting rare or dysfunctional cells, and assessing treatment regimes. The gold standard, quantitative ... -
Dynamics and Rheology of Non-colloidal Suspensions: Active and Soft Deformable Particles
Classical works on the suspensions of rigid spherical and ellipsoidal particles have been carried out by Einstein and Jeffery. However, in nature and industry, we come across materials that are either deformable or active. ... -
Experimental study of the flow of granular media through a horizontal screw feeder system
A significant fraction of the materials handled in the chemical, food-processing, and pharmaceutical industries are particulate in nature. Screw feeder systems are often employed in such scenarios to achieve their bulk ... -
FLIPP-NAAT: A paper-based LAMP assay for point-of-care TB detection
Molecular diagnostic techniques like polymerase chain reaction (PCR) revolutionized the world of healthcare. Instead of waiting for infectious agents to physically grow as in conventional culture-based tests, genetic ... -
Flow and structure of dense granular materials
Granular materials are frequently encountered in our daily lives and are widely processed forms of matter in various industries. Despite decades of research, the mechanical behavior of granular materials is not well ... -
Gravity flow of granular materials through a vertical channel
Grains and powders are the second most widely used materials in industries and daily life after simple fluids. There are a variety of granular materials such as food grains, detergents, tablets and capsules, fertilizers, ... -
Identification of crystalline structures of clathrate hydrates during molecular simulations using machine learning
Molecular simulation is a powerful tool that links a system’s microscopic behaviour to its macroscopic observable features. The data obtained from a molecular simulation act as a digital microscope, i.e., it contains ... -
Inkjet-Printed Ag Nanomaterials based Strain Sensors for Wearable Sensing Applications
Of late, the demand of wearable sensors has exponentially risen. For example, strain sensors that can be worn and are skin mountable play a significant role in the areas of human motion detection, healthcare, soft robotics, ... -
Investigating Membrane Dynamics And Oligomerization Of Pore-forming Toxins Using Single-molecule Fluorescence Techniques
The biological membrane is a thin fluidic matrix composed of a lipid bilayer that forms the primary cellular barrier against the extracellular environment. The high-density of embedded proteins and glycosylated molecules ... -
Investigation of multiscale biological phenomenon using kinetic modeling and molecular dynamics simulations
Biological systems inherently function at multiple spatial and temporal scales by integrating information across these scales. In this thesis, we are interested in investigating two classes of biological phenomena that ... -
Mesoscale Modelling of sheared lamellar mesophases
The lamellar phase or smectic lyotropic liquid crystalline medium, which is made up of alternating flat sheets of water and surfactant bilayers shearing past each other in an imposed flow. Surprisingly, In practical ... -
Micromechanical understanding of the macroscopic features of dense granular materials
The prevalence of granular materials in nature (soil, beach sand, rubble pile asteroids) and in several industries (cement, food grains, pharmaceutical powders) has motivated extensive research towards understanding the ... -
Molecular dynamics investigations of the bacterial cell envelope: Elucidating differential barriers for antimicrobials
The bacterial cell envelopes possess a complex multilayered architecture exhibiting unique properties evolved to regulate interactions with the external environment and molecules with antimicrobial properties. A molecular ... -
Molecular Dynamics simulations reveal the role of membrane cholesterol in the pore forming pathway of Cytolysin A
We investigate the interactions of pore-forming toxins (PFTs) with cholesterol-rich membranes through atomistic molecular dynamics simulations. The PFT of interest is Cytolysin A (ClyA or HlyE). Cytolysin A (ClyA), an ... -
Novel Microfluidic Tools for Multiplex Colorimetric Detection of Analytes and Point Mutation Detection in Infectious Pathogens
Recently, the need for affordable point-of-care tests has grown exponentially. An ideal point of care (POC) test or device should satisfy the WHO-endorsed ASSURED criteria, meaning that the test/device should be accessible, ... -
Paper microfluidic tools to improve the sensitivity and dynamic range of point-of-care immunoassays
Over the past decade, developing affordable home-based tests to diagnose infectious diseases has become a pressing need. The lateral flow immunoassay (LFIA) is the most successfully commercialized point-of-care immunoassay. ...