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Stochastic Models Suggest Guidelines for Protocols with Novel HIV-1 Interventions
(2018-05-25)
The treatment of human immunodeficiency virus (HIV-1) infection faces the challenge of drug resistance. The high mutation rate of HIV-1 allows it to develop resistance against all available drugs. New mechanisms of ...
Modelling How Refractoriness to Interferon Compromises Interferon-Free Treatment of Hepatitis C Virus Infection
(2018-05-25)
Hepatitis C virus (HCV) infection globally affects 130-150 million people. It causes both acute and chronic infections. Due to the severe side effects and low success rates of interferon based treatments, which formed the ...
Studies into Thermal Transmittance of Conventional and Alternative Building Materials and Associated with Building Thermal Performance
(2018-03-01)
The present investigation is focused on the thermal performance of building materials, specifically their thermal transmittance, and consequent impact on building envelope and building thermal performance. Thermal performance ...
Feature-based Approach for Semantic Interoperability of Shape Models
(2018-02-20)
Semantic interoperability (SI) of a product model refers to automatic exchange of meaning associated with the product data, among applications/domains throughout the product development cycle. In the product development ...
Development of 2D and 3D Sketching Environment to Support Early Phases of Design
(2018-04-06)
The traditional pen-paper sketching is extensively used in the early stages of product design as it supports creative exploration of product concepts and provides a fluidic mode for the expression of ideas. The Computer ...
Finite Element Modeling of Knee Joint to Study Tibio-Femoral Contact Machanics
(2018-05-10)
Articular cartilage covers the articulating ends of diarthrodial joints. It plays a vital role in the function of the musculoskeletal system by allowing almost frictionless motion to occur between the articular surfaces ...
Prediction of Physical Behavior of Rotating Blades under Tip-Rub Impact using Numerical Modeling
(2018-02-09)
Rotating blades, which are the most critical components of any turbo-machinery, need to be designed to withstand forced vibrations due to accidental tip rub impact against inner surface of casing. These vibrations are ...
Advanced Numerical Approaches for Analysis of Vehicle Ride Comfort, Wheel Bearings and Steering Control
(2018-06-23)
Suspension systems and wheels play a critical role in vehicle dynamics performance of a car in areas such as ride comfort and handling. Lumped parameter models (LPMs) are commonly used for assessing the performance of ...
Mechanical Characterization of Adhesively Bonded Jute Composite Joints under Monotonic and Cyclic Loading Conditions
(2018-03-15)
Fiber-reinforced composites comprise an important class of lightweight materials which are finding increasing applications in engineering structures including body components of automobiles and aircraft. Traditionally, ...
The Effect of Mismatch of Total Knee Replacement Components with Knee Joint : A Finite Element Analysis
(2018-01-10)
It has been noticed that the need for total knee replacement surgery is increasing for Asian region. A total knee replacement is a permanent surgical solution for a patient having debilitating pain in knee joint suffering ...