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Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding
Thesis titled, “Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding”, describes the development ...
Analytical Applications of Bile Acid-derived Soft Materials
Supramolecular gels are soft materials with solid-like properties such as supporting weight and retaining shape; and some liquid-like features which make them injectable, printable, etc. On the other hand, lanthanide-based ...
Carbon-Carbon and Carbon Heteroatom Bond Forming Reactions: From Organocatalysts to Quantum Dots
Butenolides containing stereogenic centers on the ring, are commonly encountered structural
motifs, found in many natural products. Consequently, there has been considerable interest in
efficient and stereoselective ...
Construction of C-C bonds by C-H Activation: Rh(III)-Catalyzed reactions of Arenes and Heteroarenes with Maleimides and Allylic Alcohols
The thesis presents a few Rh-catalyzed C-H activations for the construction of C-C bonds. The difficulty of substitution or the arylation at the maleimide's double bond under C-H activation conditions prompted a detailed ...
Design and Synthesis of New Delivery Vehicles for Anti- Cancer Therapeutics
The thesis entitled ‘‘Design and Synthesis of New Delivery Vehicles for Anti-Cancer Therapeutics’’ encloses the syntheses, characterization and bioactivity determination of the novel systems designed for achieving high ...
N-Heterocyclic Carbene (NHC)-Catalyzed Stereoselective Synthesis of Six-Membered Heterocycles and Carbocycles
N-Heterocyclic carbene (NHC) based catalysis is employed for the generation of α,β-unsaturated acylazoliums followed by their interception with various nucleophiles, the formal [3+3] annulation reactions for the construction ...
Construction of Carbon-Heteroatom and Heteroatom-Heteroatom bonds using Iodine and Zinc catalysts
The thesis entitled “Construction of Carbon-Heteroatom and Heteroatom-Heteroatom bonds
using Iodine and Zinc catalysts” has been divided into five chapters. Chapter 1 describes a
general introduction to iodine, hyper-valent ...
Stereoselective synthesis of functionalized allenes, total synthesis of monticolides A and B, and towards the total synthesis of tulearin C
The thesis, entitled as “Stereoselective synthesis of functionalized allenes, Total synthesis of Monticolides A and B, and towards the total synthesis of Tulearin C” is divided into two chapters.
Section A chapter-1 deals ...
Allylic Halogenation Route to Latent-Active Trans-Glycosylation of Allyl Glycoside Donors
Allylic halogenation of allyl glycosides as a new route to allyl glycoside donors in glycosylations is investigated in this thesis. Allyl functionality is one of the commonly adopted protecting groups to hydroxyl groups ...
Enantioselective Annulation Reactions: From Fischer Indolization to de novo Arene Construction
In summary, we have developed the first decarboxylative [4+2]-annulation of ethynyl
benzoxazinanones with azlactones for the enantioselective synthesis of cyclic α-quaternary
α-acylaminoamides.25 This direct and modular ...