Browsing Organic Chemistry (OC) by Advisor "Prabhakaran, Erode N"
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Design And Access To Disallowed And Unusual Conformers Of Peptides In Crystals And In Solution : Structural Consequences Of The Imidate And Thioimidate Isosteres For The Peptide Bond
(2016-03-04)This thesis entitled “Design and Access to Disallowed and Unusual Conformers of Peptides in Crystals and in Solution: Structural Consequences of the Imidate and Thioimidate Isosteres for the Peptide bond” is divided into ... -
Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding
Thesis titled, “Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding”, describes the development ... -
HBS Constrained Antiparallel β-Sheets and Flat Toroid Turns; Homoserine, Thioamide and 1,3-Thiazine Containing Peptidomimetics: Design, Synthesis, Conformational Analyses and applications
In chemical biology, short peptidomimetic biological active models have been widely used for anti-microbial activity, drug development, catalysis, and amyloidogenesis. In this thesis, I have synthesized several unnaturally ... -
Investigating the Intercarbonyl X...C' (X=O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of charge->II* Interactions. Synthesis and Characterization of Thioimidate Isostere Containing Peptidomimetics
(2018-02-06)This thesis entitled “Investigating the Intercarbonyl X···C′ (X = O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of Charge→π* Interactions. Synthesis and Characterization of Thioimidate Isostere ... -
Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins : Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond
(2017-12-03)This thesis titled, “Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins: Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond”, ...