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Photocytotoxicity And DNA Cleavage Activity Of Metal Scorpionates And Terpyridine Complexes
(2011-08-22)
Scorpionate and terpyridine ligands are of importance in inorganic chemistry for their metal-binding properties. Tris-pyrazolylborate (Scorpionate) ligands that show facial binding mode and steric protection have been ...
Aspects Of The Chemistry Of Oxovanadiulm(IV) Complexes Showing Photo-Induced Cytotoxicity And DNA Cleavage Activity
(2011-07-08)
The present thesis deals with different aspects of the chemistry of oxovanadium(IV) complexes, their interaction with DNA and protein and photo-induced DNA and protein cleavage activity and photocytotoxicity.
Chapter I ...
Ancillary Ligand Effects On The Anticancer Activity Of Ruthenium(II) Piano Stool Complexes
(2011-01-17)
The thesis “Ancillary Ligand Effects on the Anticancer Activity of Ruthenium (II) Piano Stool Complexes” is an effort to design better antitumor metallodrugs based on ruthenium(II) complexes with various H-bond donor/acceptor ...
Modelling Stochasticity In Selected Biological Processes
(2010-08-16)
Biological processes at the cellular level take place in heterogeneous environments, and usually involve only a small number of molecules. They tend to exhibit strong time dependent fluctuations, as a result, and are, ...
Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics
(2018-03-26)
Thyroxine is the main secretory hormone of thyroid gland and it is produced in thyroglobulin by thyroid peroxidase/hydrogen peroxide/iodide system. After biosynthesis and secretion of thyroxine, it undergoes multiple ...
Biomimetic Studies on Tyrosine- and Phenolate- Based Ligands and their Metal Complexes
(2017-11-14)
Tyrosine (4-hydroxyphenylalanine) is one of the naturally occurring 22 amino acids. The importance of tyrosine is due to the presence of its phenolic side chain. In biological systems, the tyrosyl residue in proteins is ...