Browsing Inorganic and Physical Chemistry (IPC) by Subject "Mitochondria"
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Photodynamic Therapy and Cellular Imaging using Platinum(II) Conjugates of Boron-dipyrromethene and Curcumin
The present thesis portrays the rational design and successful synthesis of platinum(II) complexes for achieving photoactivated dual action anticancer properties. The research project centers on synthesis, comprehensive ... -
Turning an Antioxidant into a Prooxidant: Light-induced Mitochondrial Apoptosis in Mammalian Cells by an Ergothioneine-based Neutral Small Molecule
Embargo up to Feb 28, 2026 Mitochondria-targeted compounds gained significant interest due to their applications in fundamental research, diagnostics, and therapeutics. In this work, we present a detailed investigation ... -
Vanadium Complexes for DNA Crosslinking and Photodynamic Applications
The present thesis work deals with the studies involving synthesis of vanadium-based complexes as photoactivated chemotherapeutic as well a photodynamic therapeutic agent. Their interactions with DNA, as double-stranded ...