Browsing Inorganic and Physical Chemistry (IPC) by Title
Now showing items 80-99 of 535
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Copper (I) promoted allylic nucleophilic substitution: a synthetic and mechanistic study.
Abstract not available -
Cytotoxicity of Metal Based Anticancer Active Complexes and their Targeted Delivery using Nanoparticles
(2018-02-21)Use of metal based anticancer medication began with the clinical approval of cisplatin in 1978. Research led to the development of six platinum based drug candidates which are in use around the world. However there is a ... -
Deiodination of Thyroid Hormones by Iodothyronine Deiodinase Mimics
(2018-03-26)Thyroxine is the main secretory hormone of thyroid gland and it is produced in thyroglobulin by thyroid peroxidase/hydrogen peroxide/iodide system. After biosynthesis and secretion of thyroxine, it undergoes multiple ... -
Design and Application of Self-Assembled Coordination Cages for Catalysis and as Drug Carrier
In summary the present thesis accounts for the design and synthesis of various coordination cages formed through the self-assembly reaction of the newly designed pyridine and pyrimidine based ligands with various 90° ... -
Design and Development of Hybrid Catalyst for Hydrogen Storage: A Demonstrative Concept using Liquid Organic Hydrogen Carriers (LOHCs)
The urgent need to address CO2 emissions resulting from the industrial revolution has placed a strong emphasis on the reduction of greenhouse gases. As a result, hydrogen has gained significant attention as a sustainable ... -
Design and Development of Proteasome Activity Modulators: A Novel Strategy for the Treatment of Diabetes Mellitus
Design and Development of Proteasome Activity Modulators: A Novel Strategy for the Treatment of Diabetes Mellitus Abstract The ubiquitin-proteasome system (UPS) is the major pathway for degradation of the intracellular ... -
Design and development of proteasome inhibitors with improved efficacy in breast cancer cells: 3D tissue models and detailed molecular mechanistic studies
The proteasome is an enzyme complex that regulates the degradation of intracellular proteins, maintaining cell cycle regulation, protein quality, and cellular homeostasis. Proteasome inhibition has gained popularity as a ... -
Design and Syntheses of Triarylborane Decorated Luminescent Dyes : Intriguing Optical Properties and Anion Sensing Applications
(2018-05-08)The main thrust of this thesis is the development of new triarylborane containing luminescent molecules as well as utilizing triarylboron center as a receptor for the selective detection of biologically, environmentally ... -
Design and Synthesis of Cyclic Diselenides and Selenenyl Sulfides for Biomimetic Applications
Hydrogen peroxide (H2O2) plays important roles in cell signaling and redox reactions. However, elevated levels of H2O2 and organic peroxides induce oxidative stress, resulting in damage to biomolecules such as DNA, ... -
Design And Synthesis Of Novel Angiotensin Converting Enzyme (ACE) Inhibitors Having Antioxidant Activity
(2011-08-05)Angiotensin converting enzyme (ACE) catalyzes the conversion of angiotensin I (Ang I) to angiotensin II (AngII). ACE also cleaves the terminal dipeptide of vasodilating hormone bradykinin (a nonapeptide) to its inactive ... -
Design Strategies for Janus and Core–Shell Structures and Single- Ion Conducting Membranes Based on Hyperbranched Polymers
Hyperbranched polymers (HBPs) are a class of highly branched macromolecules characterized by their low melt viscosity, high solubility, and numerous terminal functional groups amenable to chemical modification.1 Janus ... -
Design, Synthesis and Optical Characterization of 1,8-Naphthalimide based D-pi-A System
Design, Synthesis and Optical Characterization of 1,8-Naphthalimide based D-pi-A System Luminescent materials find a lot of application in the field of OLEDs and bio-medical applications [1-2]. Our group has recently ... -
Design, Synthesis and Optical Characterization of Thiophene Based Luminophore
We successfully designed and synthesized a series of thiophene based luminophores. We were able to modulate the optical band gap of these luminophores by systematically fine-tuning the chemical structure of these compounds. ... -
Design, Synthesis and photophysical studies of sigmented
Electroluminescent polymers are a novel class of conjugated polymers, which have promising potential for use in various optoelectronic devices like all-plastic displays, solar cells, lasers, etc. The species responsible ... -
Developing a tunable, adaptive plasmid selection system to screen Aminoacyl-tRNA synthetase variants
The genetic code refers to a set of rules used by living organisms to translate information encoded within the genetic material (DNA/mRNA sequences) into proteins. All organisms generally encode 22 proteinogenic or canonical ... -
Development and Applications of Portable Raman Spectroscopy Combined with Artificial Intelligence for Biomedicine
Currently, the global spectroscopic community is investigating the suitability of vibrational spectroscopy methods for point-of-care testing, histopathology, and rapid in-vivo biomedical diagnostics. Although Raman ... -
Development and Evaluation of Plasma Electrolytic Oxidation Coatings for Spacecraft Applications
Spacecraft structures are often fabricated out of light weight materials in order to reduce the overall mass, thereby reducing the launch cost and/or increasing the payload capability. Aluminium alloys, especially AA6061, ... -
Development of New Synthetic Methodologies for Selenocysteine, Selenopeptides and β-Seleno Amino Acids”
thesis mainly describes the synthesis and characterization of novel selenium-containing amino acids for their potential application in redox reactions. Several β-seleno-α-amino acids have been synthesized and fully ...