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Now showing items 6171-6190 of 8778
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Role of Chemokine Receptor, CXCR4 Mediated Signaling in Cellular Senescence
(2017-10-05)Cellular senescence has been proposed to be equivalent to organismal aging and is one of the outcomes of the cell fate decision process in response to DNA damage that occurs in cells. When a cell encounters DNA damage, the ... -
Role of Composition, Structure and Physico-Chemical Environment on Stabilisation of Kuttanad Soil
(2018-04-12)Soft soil deposits of coastal regions and lowland areas pose many geotechnical problems but it is indispensable to utilize these grounds to meet the growing demand for infrastructure with ever increasing urbanization and ... -
Role of conserved features of initiator tRNA and ribosome heterogeneity in translation initiation in Escherichia coli
Translation is one of the fundamental and core cellular processes catalysed by a ribonucleoprotein complex called ribosome. The process involves four major steps: initiation, elongation, termination and recycling. Initiation ... -
Role of Crosslinks and Fiber Reinforcement in Hydrogel Mechanics
Hydrogels are soft materials that exhibit nonlinear mechanical behavior under large deformations but can fail catastrophically, limiting their applications. Developing tough, biocompatible hydrogels with high strength and ... -
The Role of Cytoskeletal Morphology in the Nanoorganization of Synapse
(2018-01-10)Synapse is the fundamental unit of synaptic transmission. Learning, memory and neurodegenerative diseases of the brain are attributed to the maintenance and alteration in synaptic connections. The efficiency for synaptic ... -
Role of DNA Methylation in Glioblastoma Development
(2018-04-11)Glioblastoma (GBM) is the most common and malignant of the glial tumors. These tumors may develop from lower-grade astrocytomas (diffuse astrocytoma; grade II or anaplastic astrocytoma; grade III) through a progressive ... -
The Role of DNA Structural Features of Eukaryotic Promoter Sequences in Transcription Regulation
(2018-09-04)Understanding the molecular structure of DNA was considered as greatest achievement in modern biology. It helped in understanding fundamental cellular processes such as replication of DNA, nature of the ... -
Role of equatorial convection and moisture in the structure and propagation of Boreal Summer Intraseasonal Oscillations
Boreal Summer Intraseasonal Oscillation (BSISO) is the dominant mode of tropical variability during Boreal summers. BSISO is manifested by northward propagation of the Maximum Cloud Zone (MCZ) from the warm equatorial ... -
Role of Escherichia coli UvrD helicase in resolving G-quadruplex DNA structures
G-quadruplex (G4) secondary structures have been implicated in various biological processes, including gene expression, DNA replication and telomere maintenance. However, unresolved G4 structures impede replication ... -
Role of Excess Fe in Pristine and Substituted Fe Chalcogenide Superconductors
(2018-03-02)Fe chalcogenides : The discovery of superconductivity in Fe based compounds trig- gered an intense research activity in this field with significant importance given to material synthesis. As a result, numerous materials ... -
Role of Fiber Orientations in the Mechanobiology of Cells under Stretch
Fiber reinforcement plays an important role in the structure and function of biological materials. Soft connective tissues in human body like artery, heart tissues, skin etc. exhibit anisotropic material responses due to ... -
Role of Friction in Microswimmer and Active Filament Motion
Friction is pervasive in all fields of science. It is the key factor that emerging technologies involving autonomous motion at micron scales such as micro-bots need to overcome in order to be efficient. They fall in the ... -
Role of gamma oscillations in processing of natural stimuli
Gamma oscillations (~30-80 Hz) are a prominent signature of electrophysiological signals recorded from the brain with proposed roles in various cognitive functions such as attention and visual perception. Although gamma ... -
Role of Glycosylation and Oligomerization on the Stability of Soybean Agglutinin
Carbohydrates are vital to life. In their naive form, they serve as a primary energy source for supporting life. However, in most cases carbohydrates do not exist as simple sugars in nature. Instead they occur as more ... -
Role of Grp 75 Chaperone Folding Machinery in the Maintenance of Mitochondrial Protien Quality Control
(2018-04-03)My research focuses on understanding the importance of human mitochondrial Hsp70 (Grp75) chaperone machinery for the maintenance of protein quality control inside the mitochondrial matrix. The investigations carried out ... -
Role of Gypsum in Stabilisation of Expansive Soil with Lime/Fly Ash-A Micro-Mechanistic Study
Stabilization of expansive soils with various calcium–based stabilizers (lime and cement) directly or in combinations with other solid waste materials such as fly ash and ground granulated blast furnace slag (GGBS) etc. ... -
Role of HCN Currents (Ih) in Epileptiform Activity in Subicular Neurons
Subicular burst firing neurons are established as primary instigators of seizure onset and propagation in Temporal Lobe Epilepsy (TLE), a form of focal epilepsy that accounts for approximately 60% of all epilepsy cases in ...