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Now showing items 6492-6505 of 6505
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X-Ray Crystallograhic Studies On 2',5', Cyclic And Modified Nucleotides
(2007-09-05)This thesis presents the crystal structures of 2', 5', cyclic and modified nucleosides / nucleotides. Chapter I gives a brief account of the structural studies on 2', 5' and modified nucleotides. It also presents a short, ... -
X-ray Crystallographic Characterization Of Designed Peptides Containing Heterochiral And Homochiral Diproline Segments And Database Analysis
(2010-12-30)Understanding the relation between amino acid sequences and protein structures is one of the most important problems in modern molecular biology. However, due to the complexities in the protein structure, this task is ... -
X-ray Crystallographic Studies Of Designed Peptides, Self Assembling Pseudopeptides And Molecular Modeling
(2009-03-04)Structural studies of peptides has relevance for various applications, like, in de novo design of proteins, in designing better catalysts for organic synthesis, in structure based drug design, in the design and construction ... -
X-Ray Crystallographic Studies Of Designed Peptides : Characterization Of Novel Secondary Structures Of Peptides Containing Conformationally Constrained α-, β- And γ-Amino Acids And Polymorphic Peptide Helices
(2010-10-21)Structural studies of peptides are of great importance in developing novel and effective biomaterials ranging from drugs and vaccines to nano materials with industrial applications. In addition, they provide model systems ... -
X-Ray Crystallographic Studies Of Designed Peptides : Characterization Of Self-Assembled Peptide Nanotubes With Encapsulated Water Wires And β-Hairpins As Model Systems For β-Sheet Folding
(2011-08-08)The study of synthetic peptides aid in improving our current understanding of the fundamental principles for the de novo design of functional proteins. The investigation of designed peptides has been instrumental in providing ... -
X-Ray Crystallographic Studies Of Designed Peptides And Protected Omega Amino Acids : Structure, Conformation, Aggregation And Aromatic Interactions
(2009-05-18)Peptides have assumed considerable importance in pharmaceutical industry and vaccine research. Understanding the structural features of these peptide molecules can be effective not only in mimicking natural proteins but ... -
Xenopus Laevis TGF-ß: Cloning And Characterization Of The Signaling Receptors
(Indian Institute of Science, 2006-07-21)The amphibian species Xenopus laevis, along with mouse and chicken is a very important model system, used widely to dissect the molecular intricacies of various aspects of vertebrate development. Study with Xenopus has ... -
Zeolitic Imidazolate Framework (ZIF-8) Supported Nanoparticles: Synthesis and Applications
Nanoparticles have gained great interest in various fundamental and applied areas of science and technology due to their tunable size dependent properties which is not achievable by their bulk counterparts. Nanoparticles ... -
β-Keto Phoshonates from Tartaric Acid in the Total Synthesis of (+)-4-epi-gabosine A, (+)-dihydrokawain-5-ol, (-)-bengamide E and indetification of MPK-09 : A Small Molecule that Restores the Wild type Function of Mutant p53
The thesis entitled “-Keto phosphonates from tartaric acid in the total synthesis of ()-4-epi-gabosine A, ()-dihydrokawain-5-ol, ()-bengamide E and Identification of MPK-09: A small molecule that restores the wild type ...