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Now showing items 5699-5718 of 6421
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Subthreshold Conductances Regulate Theta-Frequency Local Field Potentials and Spike Phase
(2018-02-21)Local field potentials (LFPs), extracellular potentials that reflect localized electrical activity, have long been used as a window to understand the behavioural dependence and mechanistic aspects of brain physiology. A ... -
Sulfoximine and Sulfoxonium Ylide Directed C-H Activation and Domino Cyclization: Construction of Heterocyclic and Carbocyclic Rings
The thesis presents the construction of heterocyclic and carbocyclic rings using rhodium-catalyzed C-H bond activation followed by a tandem cyclization strategy. This involves the synthesis of heterocyclic compounds such ... -
Summer-Less Dual Charge Pump Based PLL With Wide Lock Range Using Analog Frequency Detector
(2011-01-18)Phase Locked Loop (PLL) is an integral component of clock generation circuits. A third order Charge Pump PLL (CPPLL) is most widely employed PLL architecture due to its zero steady state phase error. A monolithic implementation ... -
Super-Convergent Finite Elements For Analysis Of Higher Order Laminated Composite Beams
(2009-08-12)Advances in the design and manufacturing technologies have greatly enhanced the utility of fiber reinforced composite materials in aircraft, helicopter and space- craft structural components. The special characteristics ... -
Super-Resolution Imaging Reveals Localization and Regulation of Nanoscale Machinery Involved in the Amyloidogenic Pathway
Amyloid Precursor Protein (APP) is a key player in Alzheimer’s disease (AD). Despite intuitive insights into differential proteolysis of APP, there is a little understanding of how the amyloidogenic machinery is distributed ... -
Superconducting qubit-based hybrid devices
Quantum technology has potential applications in many areas of science and engineering. Recently, there has been significant progress in developing hybrid quantum devices using a superconducting qubit platform. The hybrid ... -
Superconductivity in strongly correlated systems: Heavy fermions, Cuprates, Infinite-layer Nickelates
The phase diagrams of the heavy fermion, transition-metal (copper-, nickel-) oxides materials have a wide variety of different phases. It is believed that, the strong correlation among electrons governs most of the ... -
Supercritical CO2 Power Cycles and Turbomachinery Development for Renewable Energy and Waste Heat Recovery
Supercritical carbon dioxide (sCO2) power cycles have transitioned from the kilowatt level pilot facilities to the megawatt level demonstration plants. Theoretical studies and commercial benefits associated with sCO2, such ... -
Superplastic Deformation Behaviour Of AZ31 Magnesium Alloy
(2009-05-29)Superplastic deformation behaviour of AZ31 magnesium alloy having initial grain sizes 8, 11 and 17μm alloy was investigated at 673 K with initial strain rates ranging from 1x10-2 to 1x10-4 s-1. Mechanical data on fine ... -
Superscalar Processor Models Using Statistical Learning
(2009-06-24)Processor architectures are becoming increasingly complex and hence architects have to evaluate a large design space consisting of several parameters, each with a number of potential settings. In order to assist in guiding ... -
Supervised Classification of Missense Mutations as Pathogenic or Tolerated using Ensemble Learning Methods
(2018-07-09)Missense mutations account for more than 50% of the mutations known to be involved in human inherited diseases. Missense classification is a challenging task that involves sequencing of the genome, identifying the variations, ... -
Supervised Learning Approaches for Language and Speaker Recognition
In the age of artificial intelligence, it is important for machines to figure out who is speaking automatically and in what language - a task humans are naturally capable of. Developing algorithms that automatically infer ... -
Supervised Learning of Piecewise Linear Models
(2018-03-07)Supervised learning of piecewise linear models is a well studied problem in machine learning community. The key idea in piecewise linear modeling is to properly partition the input space and learn a linear model for every ... -
Support Recovery from Linear Measurements: Tradeoffs in the Measurement-Constrained Regime
In this thesis, we study problems under the theme of discovering joint sparsity structure in a set of high-dimensional data samples from linear measurements. Our primary focus is on the regime where the number of samples ... -
Supporting Designers in Generating Novel Ideas at the Conceptual Stage Using Analogies from the Biological Domain
The aim of this research is to support designers in novel idea generation using design-by-analogy method, in particular, by using analogies from the biological domain. The motivation behind this research is to aid designers ... -
Supporting Environmentally-benign Design at Conceptual Stage
An ‘environmentally-benign design’ is defined as that which causes little or no harm to the natural environment and may be achieved by reducing the environmental impact of the design solutions conceptualised, to be ... -
Supporting Novelty In Conceptual Phase Of Engineering Design
(2013-10-08)Current design models, approaches and theories are highly fragmented, have seldom been compared with one another, and rarely attempted to be consolidated. Novelty is a measure of creativity of engineering products and ... -
Supporting Real-Time, Automated Evaluation of Difficulty in Manual Assembly
(2018-08-29)Product designers address the costs of assembly during the design process. Design process can be more efficient if assembly issues could be addressed early in its design process. Doing this requires the ability to assess ... -
Suppression of epileptiform activity by lactate through HCA1 and GIRK channel activation in rat subicular pyramidal neurons
In the present study, we report a lactate-induced hyperpolarization and reduction of epileptiform activity in subicular weak burst firing and regular firing neurons using patch clamp electrophysiology. We showed the ... -
Supramolecular Gels : Organogels, Aerogels And Tunable, Multi-color, Luminescent Hydrogels
(2014-08-06)Chapter 1: Supramolecular gels and their applications Gels are viscoelastic materials composed of a solid-like three dimensional fibrillar network that is embedded in a liquid. Supramolecular gels belong to a class of ...