Browsing by Title
Now showing items 4681-4700 of 8778
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Molecular Mechanisms Underlying Phosphatidylinositol-Specific Phospholipase C Mediated Regulation Of Lipid Metabolism
(2016-03-04)Phosphoinositide-specific phospholipase C (PLC) is involved in Ca2+ mediated signalling events that lead to altered cellular status. PLC activation causes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) and ... -
Molecular mimicry by an antiidiotypic monoclonal antibody to gonadotropin releasing hormone : Binding and signalling properties
This thesis deals with the establishment and characterization of monoclonal antibodies (mAbs) to gonadotropin-releasing hormone (GnRH) receptor, with particular emphasis on the investigations into the abilities of the mAbs ... -
Molecular Modulation Of Material Properties: Studies On Nanoparticles, Nanoassemblies, And Low Molecular-Mass Gelator
(2007-11-19)The present thesis titled “Molecular Modulation of Material Properties: Stud- ies on Nanoparticles, Nanoassemblies and Low Molecular Mass Gelator” deals with the preparation, characterization, and investigations into the ... -
Molecular pathways governing maturation and decay of precursor piRNAs in Caenorhabditis elegans
Piwi-interacting RNAs (piRNAs) are an animal-specific class of germline-enriched small non-coding RNAs that play a crucial role in germline development and fertility in diverse organisms. In Caenorhabditis elegans (C. ... -
Molecular Phenotyping of Mutations in Guanylyi Cyclase C Associated with Congenital Diarrhea
(2018-02-28)Guanylyl cyclase C (GC-C) is a member of particulate guanylyl cyclases, discovered primarily as the target of a family of heat stable enterotoxins (ST), produced by enterotoxigenic Escherichia coli (ETEC). ST is acknowledged ... -
Molecular Simulation of Anisotropic Stress and Structure in polymers
(2018-02-15)This dissertation presents a numerical study using molecular dynamic simulations that interrogates the polymer structure as it is strained continuously in time and correlates it with the stress developed in it. We investigate ... -
Molecular simulation of thermal conductivity in DNA and phonon dispersion in layered materials
Heat conduction plays a key role and is linked to the underneath lattice structure. The heat transfer in soft matter materials like DNA and polymers is seldom understood and is deeply linked to the geometry and functional ... -
Molecular Simulation Studies of Competing Pathways in Crystal Nucleation
Microscopic nature of nuclei and extremely fast nucleation events makes it difficult to study nucleation experimentally. Route to nucleation can be effected by different parameters such as thermodynamic conditions, uid ... -
Molecular Simulation Study of Electric Double Layer Capacitor With Aqueous Electrolytes
(2018-05-22)Electric double layer capacitors (EDLCs) are an important class of electrical energy storage devices which store energy in the form of electric double layers. The charging mechanism is highly reversible physical adsorption ... -
Molecular Simulations Of Temperature Induced Disorder And Pressure Induced Ordering In Organic Molecular Crystals
(2007-09-05)Crystallographically solids with well defined crystal structures are normally assumed to be highly ordered. However, it is not uncommon to find considerable degree of disorder amongst many of these crystalline substances. ... -
A molecular systems approach to unravel mechanisms and targets in antifolate-resistant bacteria and cancers
Antifolates such as trimethoprim (TMP) and methotrexate (MTX) widely used for treating bacterial infections and certain cancers respectively, inhibit dihydrofolate reductase (DHFR) in the folate pathway. However, the use ... -
Molecular Transport in Polyelectrolyte Multilayers
(2018-06-26)Layer-by-layer assembly of polyelectrolytes is a simple technique based on the self-assembly of polycations and polyanions mainly by electrostatic interactions, which has gained considerable scientific interest for its ... -
Molecularly Imprinted Polymers Based On Fluorescent And Template Binding Cross-Linker
(2013-05-23)The synthesis of materials with molecular recognition properties has become a topic of great technological and scientific interest. Molecular imprinting is one of the most effective strategies in preparing highly selective ... -
Molten-salt Synthesis Of Nanocrystalline Strontium Antimony Manganese Oxide (Sr2SbMnO6) : A Gaint Dielectric Constant Material
(2010-12-03)High dielectric constant materials are of technological importance as they lead to the miniaturization of the electronic devices. For instance, in the case of memory devices based on capacitive components, such as static ... -
Momentum And Enthalpy Transfer In Packed Beds - Experimental Evaluation For Unsteady Inlet Temperature At High Reynolds Numbers
(2013-06-10)Solid propellant gas generators that have high gas capacity are used for fast pressurization of inflatable devices or elastic shells. However, many applications such as control surface actuation, air bottle pressurization ... -
The Momentum Construction Method for Higher Extremal Kähler and Conical Higher cscK Metrics
This thesis consists of two parts. In both the parts we study two new notions of canonical K\"ahler metrics on compact K\"ahler manifolds which were introduced by Pingali, viz. `higher extremal K\"ahler metric' and ... -
Monitoring and Control of Intermittent Water Distribution Network
Millions of people in low and middle-income countries worldwide receive water only for a small fraction of the time in a day through piped networks. Even though the percentage of the world’s population with access to piped ... -
Monitoring program dynamics : Evaluation of software profiler effectiveness
Program monitoring tools are often used to verify program correctness, study program performance, and identify performance bottlenecks. Program profilers are a class of program monitoring tools which aid in tuning the ...