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Implications of Soluble Diacylglycerol Acyltransferases in Triacylglycerol Biosynthesis in Yeast and Plants
(2018-04-12)
Lipids are stored in a cell for providing energy. The main advantages of storing lipids over carbohydrates like glycogen is that, lipids yield more energy after oxidation because they represent the highly reduced form of ...
Identification of the Minimal Domain of RNA Trihosphastase Activity in the L Protien of Rinderpest Virus and Charecterization of its Enzymatic Activities
(2018-04-03)
Morbilliviruses belong to the family Paramyxoviridae of the Mononegavirale order of viruses. The Mononegavirale order contains viruses which contain negatively-polar, non-segmented and single stranded RNA genomes. This ...
Understanding the Heat Shock Response Pathway in Plasmodium Falciparum and Identification of a Novel Exported Heat Shock Protein
(2018-02-27)
Infections or diseases are not just stressful for the one who encounters it. The pathogens causing the same also have to deal with the hostile environment present in the host. The maintenance of physiological homeostatic ...
Understanding in vivo Significance of Allosteric Regulation in mtHsp70s : Revealing its Implications in Parkinson's Disease Progression
(2018-01-28)
Mitochondria are essential eukaryotic organelles, acting as the sites for numerous crucial metabolic and signalling pathways. The biogenesis of mitochondria requires efficient targeting of several hundreds of proteins from ...
Molecular Characterization of Groundnut Bud Necrosis Virus Encoded Non Structural Protein m (NSm)
(2018-01-28)
Chapter 3
Groundnut Bud Necrosis Virus (GBNV) is a tripartite ambisense RNA plant virus that belongs to serogroup IV of Tospovirus genus. Non-Structural protein-m (NSm), which functions as movement protein in tospoviruses, ...
Mxr1p is a Global Regulator of Multiple Metabolic Pathways in the Methylotrophic Yeast Pichia Pastoris
(2018-03-01)
The present study is aimed at examining the ability of Pichia pastoris to utilize acetate and amino acids as the sole sources of carbon. We demonstrate that the zinc finger transcription factor Mxr1p, which is a positive ...
Uncovering the Role of Mitochondrial Co-chaperones and Artificial Antioxidants in Cellular Redox Homeostasis
(2018-02-14)
The role of mitochondria is multidimensional and ranges in vast areas, including apoptosis, cellular response towards stress, metabolism, which is regulated by a plethora of proteins, acting together to maintain cellular ...
Cytosolic Lysophosphatidic Acid Acyltransferase : Implications in Lipid Biosynthesis in Yeast, Plants and Human
(2018-02-11)
Cytosolic LPA acyltransferase in yeast
An isooctane tolerant strain of S. cerevisiae KK-12 was reported to have increased saturated fatty acid content (Miura et. al., 2000). Amongst the various genes upregulated on isooctane ...