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Elucidating the Roles of Lon Protease and its Substrate, MarA, in Response to salicylate and other Compounds in Escherichia coli
(2017-11-28)
Cytosolic protein degradation is crucial for cellular homeostasis as it orchestrates protein turnover by destruction of misfolded, unstable and abnormal proteins. This process has two main stages: (i) an ATP-dependent stage ...
Insights Into The Mechanism Of Polyprotein Processing Of Sesbania Mosaic Virus And Characterization Of The Polyprotein Domains
(2013-06-10)
1. Viruses are obligate parasites that hijack the host cell machinery to synthesize
their own gene products and for their propagation. In order to establish a
successful viral infection, viruses have evolved different ...
Studies On Polypyrimidine Tract Binding Protein : Identification Of Interacting Partners
(2010-03-26)
PTB (HnRNP I) is a multifunctional RNA binding protein which participates in a variety of RNA metabolic processes put together called as post transcriptional gene regulation. It interacts with shuttling hnRNPs L, K and E2 ...
Effect Of Glycodelin A On Cells Of The Immune System Insights Into GdA-Induced Signaling In Monocytes, B And NK Cells
(2010-04-06)
Glycodelin is a 162 amino acid dimeric, glycosylated, secretory protein of the lipocalin superfamily. Its classification as a lipocalin(carriers of small hydrophobic molecules) is based mainly on the presence of lipocalin ...
Cytosolic Lysophosphatidic Acid Acyltransferase : Implications in Lipid Biosynthesis in Yeast, Plants and Human
(2018-02-11)
Cytosolic LPA acyltransferase in yeast
An isooctane tolerant strain of S. cerevisiae KK-12 was reported to have increased saturated fatty acid content (Miura et. al., 2000). Amongst the various genes upregulated on isooctane ...
Molecular Mechanisms Underlying Phosphatidylinositol-Specific Phospholipase C Mediated Regulation Of Lipid Metabolism
(2016-03-04)
Phosphoinositide-specific phospholipase C (PLC) is involved in Ca2+ mediated signalling events that lead to altered cellular status. PLC activation causes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) and ...
Molecular Cloning And Characterization Of A Calcium-Depdendent Protein Kinase Isoform ScCPK1 From Swainsona Canescens
(2013-06-10)
Plants are constantly exposed to pathogens and various environmental stresses, such as cold, salinity and drought. Plants normally respond rapidly to these biotic and abiotic stresses. Efficient perception of biotic and ...
Studies On The Functional Roles Of Peptidase N, A M1 Family Member, During Stress And Infection
(2014-08-11)
The cytosolic protein degradation pathway, performed by ATP-dependent proteases and ATP-independent peptidases, plays important roles in several cellular activities, e.g. cell division, cell cycle progression, intracellular ...
Glycodelin-A As The Regulator Of CD8+ T-Lymphocyte Activity : Implications In Primate Pregnancy
(2015-01-02)
The ability of our immune system to mount a response against non-self-antigens legitimates the semi-allogenic fetus as a target for maternal immune attack. Yet, in a normal pregnancy the fetus stays well protected due to ...