etd AT Indian Institute of Science: Recent submissions
Now showing items 2901-2920 of 6965
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Study of Composition & Performance of Global IT Project Teams : An Analysis of Cross-Sectional, Longitudinal & Exceptional Performances
Virtual project teams, with their members distributed across onshore-nearshore-offshore locations, have been primary units of delivery for Global IT industry. While the industry has increasingly evolved towards increased ... -
Regulation of Expression of p53 and its Isoform Δ40p53 : Consequences on Cellular Gene Expression
The TP53 tumour suppressor gene encodes for p53 protein which is the frequently altered gene in most of the cancers. p53 protein is activated in response to different stresses and plays major role in maintaining genome ... -
Discriminative Descriptors for Unconstrained Face and Object Recognition
Face and object recognition is a challenging problem in the field of computer vision. It deals with identifying faces or objects form an image or video. Due to its numerous applications in biometrics, security, multimedia ... -
The Role of Basal Ganglia and Redundancy in Supervised Motor Learning
Human sensorimotor control can achieve highly reliable movements under circumstances of noise, redundancy, uncertainty, and sensory delays. Our ability to achieve reliable and accurate movements is in the fact we have a ... -
Structural and Functional Characterisation of Small Heat Shock Protiens from Mycobacterium Marinum M
Small Heat Shock Proteins (sHSP) are ATP-independent molecular chaperones that exhibit diversity in structure, function and mode of action. They are present ubiquitously in all kingdoms of life. They function mainly by ... -
Fast High-Dimensional Filtering
Smoothing (diffusion) is a fundamental task in low-level vision and image processing. In the context of natural images, where edges (sharp discontinuities) play an important psychovisual role, the smoothing process needs ... -
Structure and Dynamics of Fluids Under Nanoscale Confinement
Fluid molecules confined between solid surfaces separated by a few nanometers are of considerable interest in nanoscience and nanotechnology as they undergo structural and dynamical transitions absent in their corresponding ... -
Modelling and Experimental Studies on Dynamic Behaviour of Electrochemical Double Layer Capacitors
lectrochemical double layer capacitors (EDLCs) can store and deliver electrical energy at high power density with long cycle life, and can absorb peak charge/discharge loads. EDLCs can be used with batteries to insulate ... -
Pranlukast as an Allosteric Inhibitor of M.Tuberculosis Ornithine Acetyltransferase : Implication Towards Novel Combinatorial Therapy
Tuberculosis (TB) is a deadly disease responsible for the death of approximately 1.5 million people each year, with the highest being from developing nations. Tuberculosis affects mostly the lungs, and other parts of the ... -
Biophysical Studies on Mycobacterium Tuberculosis σ Factor – Regulatory Protein Complexes
Adaptation to external environmental conditions is essential for the survival of a bacterial cell. Bacteria have thus evolved multiple mechanisms to sense environmental stimuli and to couple this information into an ... -
Effects of Cyclic Permutation, Glycan Removal and Aspartate Mutagenesis on Conformation of HIV-1 Envelope
It has been decades since Human Immunodeficiency Virus-1 (HIV-1) was discovered. The virus has created havoc worldwide. According to the UNAIDS 2014 Gap report, 35million people worldwide are infected with HIV-1 and yet ... -
Cellular and Molecular Features of the Response of Mycobacterium smegmatis to Rifampicin and Moxifloxacin Upon Prolonged Exposure
Bacterial persisters are a subpopulation of bacteria that can tolerate lethal concentrations of antibiotics. These are phenotypic variants that can give rise to drug‐susceptible population upon withdrawal of the antibiotic. ... -
Rotavirus Viroplasm Structure (VS) : The First Insights into the Architectural Assembly of the Viral and Host Factors in the VS"
Rotavirus is a major cause of acute gastroenteritis in infants and young children and responsible for approximately 453,000 infantile deaths per year. Rotaviruses are non-enveloped RNA viruses belonging to the Reoviridae ... -
Deciphering the Role of METTL3-Dependent m6A-epitranscriptome in Glioma Stem-like Cells
The major roadblocks in treatment for GBM are resistance to therapy and recurrence of GBM cells. Regardless of various treatment strategies, the average survival of GBM patients is poor and incidence of recurrence remains ... -
Analysis and Control of Cascades in Complex Networks
Our modern societies are best described as complex systems consisting of a large number of interacting components. Understanding the nature of these interactions is crucial, not only for gaining insights, but also for ... -
Energy Aware Synthesis of Accelerators on a Network of HyperCells
With supply voltage no longer scaling down at the same rate as transistor feature size, keeping power dissipation to practical levels while maximizing performance is becoming a challenge in future computing systems. ... -
Chemistry of Ru(II) Complexes Bearing N-heterocyclic Carbene, Hydride, and Dihydrogen Ligands : Synthesis, Mechanistic Insights, and Applications
Introduction N-heterocyclic carbenes (NHC) are strong donors and weak acceptors. Also, NHC forms strong metal-carbon bonds in metal complexes and hence complexes bearing NHC ligands are in general, thermally stable. ... -
Algorithms for Adjusted Load Flow Solutions using the Complementarity Principle
The state of a given power system i.e. voltage magnitudes and angles at all the buses can be computed using the Newton-Raphson Load Flow (NRLF) method when active power and reactive power loads are specified at all the ... -
Edge States and Effects of Disorder in Finite Graphene Sheets
The thesis endeavours to theoretically understand electronic properties of nite trapezoidal shaped graphene sheets, and understand zero energy edge states. The motivation for this thesis is recent experimental work at Low ... -
G-Protein Coupled Estrogen Receptor (hGPER)- Mediated Action of 17β-Estradiol on hTREK-1 Potassium Channel
TREK-1 is a two-pore domain potassium channel that contributes to maintenance of the resting membrane potential of a cell. TREK-1 is involved in several physiological and pathophysiological conditions like nociception, ...