etd AT Indian Institute of Science: Recent submissions
Now showing items 1101-1120 of 7198
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Non-canonical functions of lymphoid-specific proteins AID and RAG1: Understanding mechanism, regulation, and implications in genomic instability
Recombination-activating genes (RAGs) and Activation-induced cytidine deaminase (AID) are lymphoid cell-specific proteins that play crucial roles in the development of adaptive immunity. Diversification of the immune system ... -
On the Optimality of Generative Adversarial Networks — A Variational Perspective
Generative adversarial networks (GANs) are a popular learning framework to model the underlying distribution of images. GANs comprise a min-max game between the generator and the discriminator. While the generator transforms ... -
Transport and criticality in topological systems and spin models
This thesis presents work done on transport in topological insulators and graphene-based systems, and quantum criticality in one- and two-dimensional spin models. In particular we study the following: transport on surfaces ... -
Direct Numerical Simulation of Square Vortex Flows
Atmospheric and oceanic flows are often modeled as two-dimensional due to their large planar extents (∼ 1000 km) and small vertical extent (∼ 10 km). Most phenomena in these systems are governed by the theory of two-dimensional ... -
Supervised Learning Approaches for Language and Speaker Recognition
In the age of artificial intelligence, it is important for machines to figure out who is speaking automatically and in what language - a task humans are naturally capable of. Developing algorithms that automatically infer ... -
Hydrodynamic stability of shear flows : Jet in crossflow, particle laden planar and swirling jets
Jet in crossflow is a flow scenario that involves momentum exchange of a round jet injected into a crossflow. This flow configuration has industrial importance because of its application in gas turbine combustors which ... -
Towards the development of open-chip digital microfluidics platform
Manipulating and utilizing fluid flows at microscale provides several opportunities towards technological advancement in different domains such as (but not limited to) lab-on-chip devices for mimicking biological laboratory ... -
Understanding the mechanisms of polarity establishment and nuclear envelope breakdown in Caenorhabditis elegans embryos
Polarity establishment is critical for the development and stem cell lineages. The one-cell stage of the Caenorhabditis elegans embryo polarizes soon after fertilization. As a result, the first division of the embryo ... -
Robust Numerical Modeling of Adhesively-Bonded Joints for Safety Assessment of Vehicle Body Structures Subjected to Extreme Loading
Continuous adhesively-bonded joints can lead to stiffer vehicle body structures in contrast to conventional spot-welded steel sheet metal-based unitized vehicle body design. For a given target stiffness, adhesive bonding, ... -
Genetic and environmental determinants of swarming in Pseudomonas aeruginosa
Swarming, in bacteria, is a type of group translocation phenomenon observed in several flagellated species characterized by their ability to spread across solid or semi-solid surfaces rapidly – often with a distinct colony ... -
Dynamical systems biology approach to identify mediators of the Epithelial-Hybrid-Mesenchymal spectrum
Cancer metastasis – the spread of cancer cells from one organ to another – remains the major cause of cancer-related deaths. A hallmark of metastasizing cells is their ability to adapt quickly and reversibly to their dynamic ... -
Effect of High Pressure Torsion Processing on Precipitate Containing Alloys
Severe plastic deformation (SPD) processes yield excellent grain refinement in metallic materials by application of very large shear strains while retaining the initial sample dimensions. Its effects on simultaneously ... -
Design Principles of Phenotypic Robustness and Plasticity in Gene Regulatory Networks underlying Cancer Metastasis
Metastasis – the process of cancer cells leaving the primary tumor and colonizing multiple organs – remains a major cause of cancer mortality. However, it is a highly inefficient process with only 0.01% of disseminated ... -
Growth of hole-conducting Cu2O & CuO semiconductors using CVD for next-generation electronic devices: Thin Films Transistors, Memristors, and Gas Sensors
Semiconducting oxides with visible-range transparency and high electrical conductivity have tremendous potential for transparent CMOS devices. Oxide semiconducting materials are a good choice for emerging transparent ... -
Chemistry of bimetallic, chalcogenide and highly reactive metal nanoparticles
The remarkable modifications in the characteristics of materials on a nanoscale, caused by surface effects, quantum confinement, and dependence on shape, leads to diverse applications of nanomaterials, such as in catalysis, ... -
Algorithms for Geometric Packing and Covering Problems
We study two fundamental problems related to geometric packing and covering, and design algorithms with improved worst-case performance guarantees for them. These problems have numerous applications in resource allocation, ... -
Structural and Electrochemical Investigations of Monovalent and Divalent Aqueous Rechargeable Batteries
Several stringent laws and regulations have been enforced by various National/International agencies for the adoption of sustainable methods for energy production and usage. In recent times, electric grids based on alternative ... -
Global gyrokinetic simulations of electrostatic microturbulent transport in LHD stellarator and ADITYA-U tokamak
Tokamak and stellarator are two leading contenders in the quest to achieve nuclear fusion from magnetically-confined plasmas. They differ in terms of magnetic field structure in the toroidal direction. Irrespective of the ... -
Quantum oscillation in band insulators and properties of non-equilibrium steady states in disordered insulators
Starting with the experiment on Kondo insulator SmB6 , which shows 1/B-periodic oscillations despite the absence of gapless electronic excitations in bulk, the candidate insulators showing quantum oscillation (QO) are on ... -
Solving The Unsolved In Multicomponent Diffusion: The Concept Of Constrained Diffusion Couple Methods
Quantitative diffusion analysis in multicomponent metallic systems has been a formidable task historically and despite decades of research, most of the diffusivity estimations were limited to interdiffusion and some intrinsic ...