etd AT Indian Institute of Science: Recent submissions
Now showing items 1081-1100 of 6867
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On late stages of transition in round jets
A round jet is one of the simplest canonical axisymmetric free shear flows that occur both in engineering applications and natural phenomena. A laminar-turbulent transition process is inherent to its development involving ... -
Thermodynamics of Protein Adsorption on Gold and Silica Nanoparticles
Nanoparticle-based biomedical applications in disease diagnostics, site targeting, drug delivery, etc., have been pursued vigorously with the hope of finding better solutions than conventional diagnostics and therapeutics. ... -
Deep learning methods for light fluence compensation in two-dimensional and three-dimensional photoacoustic imaging
Photoacoustic imaging (PAI) employed the special properties of light or photons to obtain detailed images of organs, tissues, cells, and even molecules. The method allowed for a non-invasive or minimally invasive examination ... -
Understanding the Long-term Impact and Mechanism of Action of Endosulfan, an Organochlorine Pesticide on Fertility, Development and Growth of Mice
Endosulfan (ES) is one of the major broad-spectrum organochlorine pesticides categorized as Class II (moderately hazardous) by WHO and Class I (highly acutely toxic) by US Environment Protection Agency. Although the use ... -
An Experimental Investigation of Transitional and Turbulent Channel Flow
This thesis is a comprehensive experimental investigation of transitional and turbulent channel flow in the Reynolds number range of Reτ = 55 − 1559. Towards this objective, a new channel flow facility was designed and ... -
Improved Understanding of Standing Waves in Single Layer Coils and Elegant Methods to Estimate Transformer Winding Parameters
Analyzing the effect of impulse voltages (like lightning, switching) on transformer winding has occupied centerstage in core electrical engineering research for over a century. These investigations gather great significance ... -
Structural insights into assembly and regulation of HigBA toxin-antitoxin system from Escherichia coli
In the last few decades, bacterial Toxin-antitoxin (TA) systems have been identified to play crucial roles in bacterial survival under stressful conditions and virulence. TA systems are pair of genetic elements where one ... -
Landmark Estimation and Image Synthesis Guidance using Self-Supervised Networks
The exponential rise in the availability of data over the past decade has fuelled research in deep learning. While supervised deep learning models achieve near-human performance using annotated data, it comes with an ... -
Towards Robust and Scalable Video Surveillance: Cross-modal and Domain Generalizable Person Re-identification
With rapid technological advances, one can easily find video surveillance systems deployed in public places such as malls, airports etc. as well as across private residential areas. These systems play a critical role in ... -
Investigation of Psychrophilic SUMO Proteases: Towards a More Efficient SUMO Protease at Lower Temperature
Covalent attachment of the fusion protein, Small Ubiquitin-like modifier (SUMO), to recalcitrant target proteins (especially transmembrane proteins) make purification of the target protein much easier by enhancing its ... -
Investigating Mechanical Properties of Suspended Ovarian Cancer Cells and Clusters
The peritoneal cavity of a patient suffering from advanced epithelial ovarian cancer is filled with disseminated multicellular aggregates, commonly known as spheroids. These spheroids colonize abdominal organs leading to ... -
Low delay file transmissions over power constrained quasi-static fading channels
The ubiquitous deployment of battery-operated wireless devices has resulted in the need for efficient low latency power allocation schemes. A common phenomenon in wireless transmission systems is congestion, where the ... -
Approaches to Regional Analysis of Hydro-Meteorological Processes and Extremes
Regional analysis of hydrometeorological variables (e.g., evapotranspiration, precipitation), hydrological processes (e.g., runoff), and their extremes (e.g., drought, floods) is essential for various applications. The ... -
Studies on BODIPY Appended Ruthenium(II) Complexes for Bioimaging and Photodynamic Therapy Applications
Photodynamic therapy (PDT) is a medical technique that utilizes light, oxygen, and a photosensitizer to treat several medical conditions, including cancer. Because of the limitations and side effects of traditional anticancer ... -
Prediction of Dynamical Systems by Constraining the Dynamics on the Observational Manifold
Evolution models of dynamical systems posed as differential equations generally do not include all the factors affecting the system. This leads to a mismatch between the model prediction and the observations. In this work, ... -
Relating Representations in Deep Learning and the Brain
Deep Neural Networks (DNN) inspired by the human brain have redefined the state-of-the-art performance in AI during the past decade. Much of the research is still trying to understand and explain the function of these ... -
Analysis of vocal sounds in asthmatic patients
Around 334 million people have asthma worldwide. Asthma is an inflammatory disease of the airways which causes cough, breathlessness, chest tightness, and other peculiar sounds during breathing. The golden standard test ... -
Investigations on Capacitor Size Reduction and PWM Strategy for Multilevel Polygonal Space Vector Structure for Induction Motor Drives
Multilevel voltage source inverter transformed conversion of DC to AC for medium to high power application. With increasing electric power demand, the multilevel converter allows high power density converters for medium ... -
Deploying an Orthogonal Turn for Isolation of Rare Cell Populations from Vascular Environments
Cancer cells are shed from metastatic primary tumors, bearing the potential for blood-borne metastasis to distant vital organs. Metastasis is predominantly responsible for cancer-related deaths. These circulating tumor ... -
Insights into the conformational stability & pharmacology of peptides through side chain and backbone modification
The first part of the work presented in the thesis deals with CH-pi interaction, which is a lesser-known non-covalent interaction in proteins. We identified several CH-pi donor-acceptor pairs involving amino acids side ...