Department of Developmental Biology & Genetics (DBG, earlier called MRDG): Recent submissions
Now showing items 121-140 of 149
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A Novel Family Of Soluble Diacylglycerol Acyltransferases
(2011-10-04) -
Studies On Intracrine Regulators Of Ovarian Function : Examination Of Progesterone Action On Structure And Function Of Corpus Luteum In The Monkey
(2011-08-09)The control of reproductive cycles in higher primates is largely dependent on negative and positive feedback mechanisms by both steroidal and non-steroidal substances of the ovaries which regulate the function of ... -
Characterization Of Down Regulated Genes In Astrocytoma
(2011-07-27)Gliomas are the most common primary brain tumors and include astrocytomas, oligodendrogliomas and oligoastrocytomas. Astrocytomas have a high frequency of occurrence as compared to the other gliomas and several studies ... -
A Study Of The Roles Played By The Trishanku Gene In The Morphogenesis Of Dictyostelium Discoideum
(2011-02-22)A hallmark feature of Dictyostelium development is the establishment and maintenance of precise cell-type proportions. In the case of D. discoideum, roughly 20% of the cells that aggregate form the stalk while the remaining ... -
Molecular Characterization Of The SLC22A18AS Gene From The Imprinted Human Chromosome Segment 11p15.5
(2011-02-21)The imprinting status of the SLC22A18AS gene, located in the human chromosome segment 11p15.5, was studied using PCR-SSCP analysis and fetal tissues from a battery of 17 abortuses. This gene showed monoallelic expression ... -
Epigenetic Regulators Of Development In The Social Amoeba Dictyostellium Discoideum : The Roles Played By Histone Deacetylases And Heat Shock Protein 90
(2011-01-20)The major evolutionary transition from single-celled to multicellular life is believed to have occurred independently of the main metazoan lineages in the cellular slime moulds, of which Dictyostelium discoideum is the ... -
Characterization Of Human Mammary Stem Cells Grown As Mammospheres
(2011-01-11)Adult stem cells are a small population present within several tissues of an individual, possessing two unique properties: one, the ability to differentiate to give rise to all the cell types of the tissue, and second, the ... -
Biochemical And Functional Characterization Of Evolutionarily Conserved Metallophosphoesterases The 239FB/AB Family
(2010-12-30)With the advent of large scale genome sequencing efforts along with more sophisticated methods of genetic mapping, a number of loci have been identified that are associated with human diseases. Intriguingly, many genes ... -
Aromatic Beta-Glucoside Utilization In Shigella Sonnei : Comparison With The Escherichia Coli Paradigm
(2010-12-01)The aromatic beta-glucosides of plant origin, salicin and arbutin, serve as carbon sources for the sustenance of bacteria when ‘preferred’ sugars are absent in the environment. In the family Enterobacteriaceae, there are ... -
Studies On Growth And Development Of The Ovarian Dominant Follicle In Monovulatory Species : Analysis Of Transcriptional Changes And Factors Influencing Periovulatory Events
(2010-10-28)In response to LH surge, the selected dominant follicle undergoes a series of complex events viz., meiotic maturation of the oocyte, terminal differentiation of follicular cells, cumulus expansion and follicular rupture ... -
Identification Of Domains Of The Follicle Stimulating Hormone Receptor Involved In Hormone Binding And Signal Transduction
(2010-10-08)The glycoprotein hormones, Luteinizing Hormone (LH), human Chorionic Gonadotropin (hCG), Follicle Stimulating Hormone (FSH) and Thyroid Stimulating Hormone (TSH) are heterodimeric proteins with an identical α-subunit ... -
Mapping Of Glycoprotein Hormone-Receptor Interactions Using Hormone Analogs And Antibodies
(2010-09-21)The glycoprotein hormone family comprising of Luteinizing Hormone (LH), Chorionic Gonadotropin (hCG), Follicle Stimulating Hormone (FSH) and Thyroid Stimulating Hormone (TSH) plays important role in reproduction and overall ... -
Human Spermatogenesis : Differential Gene Expression And Regulation
(2010-08-24)Spermatogenesis is a complex process of male germ cell development in which the diploid spermatogonia undergo series of mitotic divisions and differentiation steps culminating into the preleptotene spermatocytes which then ... -
Molecular Actions Of Arecoline, An Alkaloid Implicated In The Manifestation Of Oral Submucous Fibrosis (OSMF)
(2010-07-21)The pathogenesis of oral submucous fibrosis (OSMF) is due to a complex interplay between the production and degradation of extracellular matrix (ECM) protein components. In tissue fibrosis, there is a net accumulation of ...