Browsing Molecular Reproduction, Development and Genetics (MRDG) by Subject "Research Subject Categories::MEDICINE"
Now showing items 1-3 of 3
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Epithelial-to-mesenchymal transition and cellular cooperation in cancer progression: Novel roles for AMPK
Epithelial-mesenchymal transition (EMT) is a developmental program hijacked by cancer cells to facilitate metastasis —a multi-step process involving the spread of cancer cells from the primary tumor site and culminating ... -
Mechanism of β-catenin regulation by IGFBP2: Role in Glioblastoma progression
Insulin-like growth factor binding proteins (IGFBPs) were initially identified as high affinity binders of Insulin-like growth factors (IGFs). There are six IGFBPs which regulate the bioavailability and functions of IGFs ... -
Role of Lysyl oxidase in TGF-beta-induced Fibroblast Activation and Cancer-Associated Fibroblast-mediated Breast Cancer Progression
Cancer-associated Fibroblasts (CAFs) are a dominant cell type of the breast cancer microenvironment and are proposed to be involved in metastatic progression. TGF-β has been reported to influence fibroblast to myofibroblast ...