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    Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Subject 
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    • Division of Biological Sciences
    • Department of Developmental Biology & Genetics (DBG, earlier called MRDG)
    • Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Subject
    •   etd@IISc
    • Division of Biological Sciences
    • Department of Developmental Biology & Genetics (DBG, earlier called MRDG)
    • Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Subject
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    Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Subject "Research Subject Categories::MEDICINE"

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      • Development of patient-derived tumor models toward understanding disease biology and drug screening 

        De, Tamasa
        Cancer is a complex disease of uncontrolled cell proliferation, which cripples the normal functioning of tissues. According to GLOBOCAN 2020, an estimated 19.3 million new cancer cases and around 10 million cancer deaths ...
      • Epithelial-to-mesenchymal transition and cellular cooperation in cancer progression: Novel roles for AMPK 

        Deshpande, Neha Umakant
        Epithelial-mesenchymal transition (EMT) is a developmental program hijacked by cancer cells to facilitate metastasis —a multi-step process involving the spread of cancer cells from the primary tumor site and culminating ...
      • Investigating the role of miR-198 in oral squamous cell carcinoma pathogenesis 

        Kaushik, Pankhuri
        Evidence supports the critical role of microRNA (miRNA) dysregulation in several diseases including cancers. The aberrant expression of numerous tumor suppressor and oncogenic miRNAs is a well-established driving factor ...
      • Mechanism of β-catenin regulation by IGFBP2: Role in Glioblastoma progression 

        Verma, Brijesh Kumar
        Insulin-like growth factor binding proteins (IGFBPs) were initially identified as high affinity binders of Insulin-like growth factors (IGFs). There are six IGFBPs which regulate the bioavailability and functions of IGFs ...
      • Role of Lysyl oxidase in TGF-beta-induced Fibroblast Activation and Cancer-Associated Fibroblast-mediated Breast Cancer Progression 

        Gandhi, Armin
        Cancer-associated Fibroblasts (CAFs) are a dominant cell type of the breast cancer microenvironment and are proposed to be involved in metastatic progression. TGF-β has been reported to influence fibroblast to myofibroblast ...

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