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    Browsing Molecular Reproduction, Development and Genetics (MRDG) by Advisor 
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    • Molecular Reproduction, Development and Genetics (MRDG)
    • Browsing Molecular Reproduction, Development and Genetics (MRDG) by Advisor
    •   etd@IISc
    • Division of Biological Sciences
    • Molecular Reproduction, Development and Genetics (MRDG)
    • Browsing Molecular Reproduction, Development and Genetics (MRDG) by Advisor
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    Browsing Molecular Reproduction, Development and Genetics (MRDG) by Advisor "Rangarajan, Annapoorni"

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      • Characterization Of Human Mammary Stem Cells Grown As Mammospheres 

        Dey, Devaveena (2011-01-11)
        Adult stem cells are a small population present within several tissues of an individual, possessing two unique properties: one, the ability to differentiate to give rise to all the cell types of the tissue, and second, the ...
      • Deciphering the Mechanisms of AMPK Activation upon Anchorage- Deprivation 

        Sundararaman, Ananthalakshmy (2018-01-07)
        AMP-activated protein kinase (AMPK) is a key regulator of energy homeostasis in cells. It has been implicated as a therapeutic target for various metabolic diseases like type II diabetes and obesity. However, its role in ...
      • Epithelial-to-mesenchymal transition and cellular cooperation in cancer progression: Novel roles for AMPK 

        Deshpande, Neha Umakant
        Epithelial-mesenchymal transition (EMT) is a developmental program hijacked by cancer cells to facilitate metastasis —a multi-step process involving the spread of cancer cells from the primary tumor site and culminating ...
      • Investigating the mechanisms of cancer drug resistance 

        Jain, Ipsa
        Clinical chemo-resistance has posed a challenge to scientists and clinicians since the development of chemotherapeutics as anticancer strategy. Mechanisms of drug resistance continue to be a subject investigation amongst ...
      • Molecular insights into AMP-activated protein kinase (AMPK)-mediated regulation of anoikis resistance 

        Kumar, Saurav
        Our study identifies negative cross-talk between AMPK and two important cellular kinases, Akt and Erk. AMPK-mediated inhibition of these two kinases promotes survival of cancer cells in the matrix-deprived condition. ...
      • Regulation of Notch signalling by hypoxia and AMPK in breast cancer 

        Lahiry, Mohini
        Developmental pathways such as Notch are known to regulate self-renewal and cell fate decisions in embryonic and adult tissue-specific stem cells, while deregulation of Notch signalling is associated with malignant ...
      • Role of AMP-Activated Protein Kinase in Cancer Cell Survival under Matrix-Deprived Conditions 

        Saha, Manipa (2018-07-19)
        Cancer progression is a multi-step process requiring cells to acquire specific properties that aid the neoplastic growth. One such property is the ability to survive in the absence of matrix-attachment, a critical necessity ...
      • Stress Signaling In Development And Carcinogenesis : Role Of AMP-Activated Protein Kinase 

        Kumar, Hindupur Sravanth (2013-08-05)
        Rapidly growing tumor cells outgrow their blood supply resulting in a microenvironment with reduced oxygen and nutrients. Using an in vitro transformation model we found that cancer cells expressing the SV40 ST antigen ...

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