Browsing Molecular Reproduction, Development and Genetics (MRDG) by Advisor "Gayen, Srimonta"
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Investigating the maintenance of X- chromosome inactivation in extra-embryonic endoderm and epiblast stem cells
In eutherian female mammals, one of the X-chromosomes gets inactivated to compensate for the expression dosage of X-linked genes between the sexes. X-chromosome inactivation (XCI) serves as a paradigm of epigenetic memory ... -
Role of 3D-organization of the X-inactivation centre in imprinted X-chromosome inactivation
The connection between 3D-genome organization and genome regulation is one of the fundamental questions in modern biology. In a nucleus, the genome is organized through different layers of 3D-organization such as ...