X-ray crystallographic studies of a cytoprotective agent cyclolinopeptide: a cyclic nanopeptide

Abstract

The database analysis thus interestingly shows that the conformation observed at the active site in CLPA and antamanide is a preferred conformation observed in other oligopeptides and proteins as well. From the Leu–Leu analyses we can conclude that although the conformation of oligopeptides in crystals is severely constrained by strong packing forces, specific geometries of weak interactions still exist.