| dc.contributor.advisor | Eswarappa, Sandeep M | |
| dc.contributor.author | Kar, Debaleena | |
| dc.date.accessioned | 2024-01-04T10:23:33Z | |
| dc.date.available | 2024-01-04T10:23:33Z | |
| dc.date.submitted | 2023 | |
| dc.identifier.uri | https://etd.iisc.ac.in/handle/2005/6363 | |
| dc.description.abstract | Mammalian mRNAs generally have a 5'UTR (untranslated region), a coding DNA
sequence, and a 3'UTR. The 3'UTR of mRNA is generally believed to be the
untranslated region of the mRNA. However, there are certain instances in which the
3'UTR of mRNA can be translated. Among these are intriguing mechanisms such as
Stop Codon Readthrough (SCR) and initiation of translation in a downstream open
reading frame (ORF). These two mechanisms are the focus of study in this thesis. | en_US |
| dc.language.iso | en_US | en_US |
| dc.relation.ispartofseries | ;ET00375 | |
| dc.rights | I grant Indian Institute of Science the right to archive and to make available my thesis or dissertation in whole or in part in all forms of media, now hereafter known. I retain all proprietary rights, such as patent rights. I also retain the right to use in future works (such as articles or books) all or part
of this thesis or dissertation | en_US |
| dc.subject | Mammalian mRNAs | en_US |
| dc.subject | stop codon readthrough | en_US |
| dc.subject | open reading frame | en_US |
| dc.subject | ZNF607 | en_US |
| dc.subject | Translation | en_US |
| dc.subject | Elongation | en_US |
| dc.subject | Termination | en_US |
| dc.subject | mRNA | en_US |
| dc.subject.classification | Research Subject Categories::NATURAL SCIENCES::Chemistry::Biochemistry | en_US |
| dc.title | Translation in the 3'Untranslated Region of Mammalian Transcripts | en_US |
| dc.type | Thesis | en_US |
| dc.degree.name | PhD | en_US |
| dc.degree.level | Doctoral | en_US |
| dc.degree.grantor | Indian Institute of Science | en_US |
| dc.degree.discipline | Faculty of Science | en_US |
